Name: Glatiramer acetate
Brand: Creative Peptides
SKU: 10-101-164
Availability: MadeToOrder

Specification Technical Data Publications Customer reviews and Q&A

Synonyms/Alias	COP-1;Copolymer-1;Copoylmer 1
M.F/Formula	C254H422N70O72
M.W/Mr.	7000.0 Da (range 5000-9000)
Sequence	EAYKAAEKAYAAKEAAKEAAKAKAEKKAAYAKAKAAKYEKKAKKAAAEYKKK
Labeling Target	HLA class II histocompatibility antigen, DRB1-1 beta chain
Application	Glatiramer is for reduction of the frequency of relapses in patients with Relapsing-Remitting Multiple Sclerosis.
Activity	Binder
Biological Activity	Glatiramer acetate, a synthetic analogue of myelin basic protein and an immunomodulating agent, can be used for the research of multiple sclerosis. Glatiramer acetate exhibits strong and promiscuous binding to MHC molecules and consequent competition with various myelin antigens for their presentation to T cells.
Areas of Interest	Neurological Disease
Functions	Virus receptor activity

Source#	Synthetic
Organism	Human
InChI	InChI=1S/C9H11NO3.C6H14N2O2.C5H9NO4.C3H7NO2.C2H4O2/c10-8(9(12)13)5-6-1-3-7(11)4-2-6;7-4-2-1-3-5(8)6(9)10;6-3(5(9)10)1-2-4(7)8;1-2(4)3(5)6;1-2(3)4/h1-4,8,11H,5,10H2,(H,12,13);5H,1-4,7-8H2,(H,9,10);3H,1-2,6H2,(H,7,8)(H,9,10);2H,4H2,1H3,(H,5,6);1H3,(H,3,4)/t8-;5-;3-;2-;/m0000./s1
InChI Key	FHEAIOHRHQGZPC-KIWGSFCNSA-N
Isomeric SMILES	C[C@@H](C(=O)O)N.CC(=O)O.C1=CC(=CC=C1C[C@@H](C(=O)O)N)O.C(CCN)C[C@@H](C(=O)O)N.C(CC(=O)O)[C@@H](C(=O)O)N
BoilingPoint	385.2ºC at 760mmHg
Melting Point	N/A

1. SERS spectrum of the peptide thymosin‐β4 obtained with Ag nanorod substrate

2. Myotropic activity of allatostatins in tenebrionid beetles

3. A possible role of tachykinin-related peptide on an immune system activity of mealworm beetle, Tenebrio molitor L

4. Application of human liver organoids as a patient-derived primary model for HBV infection and related hepatocellular carcinoma

5. The effect of sex on immune responses to a homocitrullinated peptide in the DR4-transgenic mouse model of Rheumatoid Arthritis

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Glatiramer acetate

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