Name: Glatiramer acetate
Brand: Creative Peptides
SKU: 10-101-164
Availability: MadeToOrder

Specification Technical Data Publications Customer reviews and Q&A

Synonyms/Alias	COP-1;Copolymer-1;Copoylmer 1
M.F/Formula	C254H422N70O72
M.W/Mr.	7000.0 Da (range 5000-9000)
Sequence	EAYKAAEKAYAAKEAAKEAAKAKAEKKAAYAKAKAAKYEKKAKKAAAEYKKK
Labeling Target	HLA class II histocompatibility antigen, DRB1-1 beta chain
Application	Glatiramer is for reduction of the frequency of relapses in patients with Relapsing-Remitting Multiple Sclerosis.
Activity	Binder
Biological Activity	Glatiramer acetate, a synthetic analogue of myelin basic protein and an immunomodulating agent, can be used for the research of multiple sclerosis. Glatiramer acetate exhibits strong and promiscuous binding to MHC molecules and consequent competition with various myelin antigens for their presentation to T cells.
Areas of Interest	Neurological Disease
Functions	Virus receptor activity

Source#	Synthetic
Organism	Human
InChI	InChI=1S/C9H11NO3.C6H14N2O2.C5H9NO4.C3H7NO2.C2H4O2/c10-8(9(12)13)5-6-1-3-7(11)4-2-6;7-4-2-1-3-5(8)6(9)10;6-3(5(9)10)1-2-4(7)8;1-2(4)3(5)6;1-2(3)4/h1-4,8,11H,5,10H2,(H,12,13);5H,1-4,7-8H2,(H,9,10);3H,1-2,6H2,(H,7,8)(H,9,10);2H,4H2,1H3,(H,5,6);1H3,(H,3,4)/t8-;5-;3-;2-;/m0000./s1
InChI Key	FHEAIOHRHQGZPC-KIWGSFCNSA-N
Isomeric SMILES	C[C@@H](C(=O)O)N.CC(=O)O.C1=CC(=CC=C1C[C@@H](C(=O)O)N)O.C(CCN)C[C@@H](C(=O)O)N.C(CC(=O)O)[C@@H](C(=O)O)N
BoilingPoint	385.2ºC at 760mmHg
Melting Point	N/A

1. Extended exenatide administration enhances lipid metabolism and exacerbates pancreatic injury in mice on a high fat, high carbohydrate diet

2. cRGD-functionalized, DOX-conjugated, and 64Cu-labeled superparamagnetic iron oxide nanoparticles for targeted anticancer drug delivery and PET/MR imaging

3. Adipose tissue is a key organ for the beneficial effects of GLP-2 metabolic function

5. Cell-based adhesion assays for isolation of snake venom’s integrin antagonists

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Glatiramer acetate

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