Tripeptide-29

Tripeptide-29 is a synthetic peptide composed of three amino acids, designed for use in cosmetic formulations targeting skin care applications. Recognized for its role in supporting the skin's extracellular matrix, Tripeptide-29 is valued for its ability to help maintain skin texture and resilience. This ingredient is suitable for a wide range of topical products, including serums, creams, and lotions, and is compatible with global cosmetic regulations.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CPC1682

CAS No:2239-67-0

Synonyms/Alias:H-Gly-Pro-Hyp-OH;2239-67-0;Glycylprolylhydroxyproline;Tripeptide-29;Tripeptide 29;X6346H6PUM;L-Proline, glycyl-L-prolyl-4-hydroxy-, (4R)-;(2S,4R)-1-[(2S)-1-(2-aminoacetyl)pyrrolidine-2-carbonyl]-4-hydroxypyrrolidine-2-carboxylic acid;(2S,4R)-1-(((2S)-1-(Aminoacetyl)-2-pyrrolidinyl)carbonyl)-4-hydroxy-2-pyrrolidinecarboxylic acid;H-Gly-Pro-Hyp-OH (acetate);(2S,4R)-1-((S)-1-(2-Aminoacetyl)pyrrolidine-2-carbonyl)-4-hydroxypyrrolidine-2-carboxylic acid;glycyl-prolyl-hydroxyproline;MFCD00037343;UNII-X6346H6PUM;SCHEMBL3942552;CHEBI:193240;SZEOBSAZWJLOGY-VGMNWLOBSA-N;DTXSID801311276;HY-A0299;DA-74148;FG109052;CS-0137730;G77515;

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cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C12H19N3O5
M.W/Mr.
285.3
Sequence
One Letter Code:GPX
Three Letter Code:H-Gly-Pro-Hyp-OH
Functions
Tripeptide 29 is a three chain amino acid shown to increase fibroblast activity for collagen I synthesis by 400 percent. This increase in support within the skin minimizes the look of fine lines and wrinkles.

Mechanism of Action (MOA)

Tripeptide-29 is a synthetic signal peptide composed of three amino acids that interacts with skin cells to support extracellular matrix dynamics. By mimicking specific sequences found in native collagen, it can modulate cellular signaling pathways related to collagen synthesis and turnover. This peptide is understood to influence fibroblast activity, thereby contributing to the maintenance of the skin's structural proteins through non-therapeutic, biomimetic mechanisms. Suitable for use in cosmetic formulations.

Tripeptide-29 is suitable for incorporation into a variety of cosmetic formulations.

- Facial creams and lotions
- Eye contour products
- Serums and concentrates
- Sheet masks and hydrogel patches
- Leave-on gels
- After-sun skincare products
- Makeup primers

INCIName
TRIPEPTIDE-29
InChI
InChI=1S/C12H19N3O5/c13-5-10(17)14-3-1-2-8(14)11(18)15-6-7(16)4-9(15)12(19)20/h7-9,16H,1-6,13H2,(H,19,20)/t7-,8+,9+/m1/s1
InChI Key
SZEOBSAZWJLOGY-VGMNWLOBSA-N

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