Tripeptide-1 (Kollaren) is a synthetic peptide composed of three amino acids designed for use in cosmetic formulations. Recognized for its role in supporting the skin's extracellular matrix, Tripeptide-1 is commonly incorporated into anti-aging and skin conditioning products. Its inclusion aims to enhance the appearance of skin firmness and elasticity, making it suitable for a wide range of facial and body care applications within global regulatory frameworks.
Mechanism of Action (MOA)
Tripeptide-1 (kollaren) is a signal peptide that interacts with cellular receptors to support extracellular matrix dynamics. By mimicking fragments of collagen, it can influence fibroblast activity through biochemical signaling pathways, notably the TGF-β pathway. This interaction may contribute to the regulation of collagen synthesis and matrix remodeling processes. Tripeptide-1's signaling properties are utilized in cosmetic formulations to enhance the appearance of skin texture and resilience.
Tripeptide-1 (Kollaren) can be incorporated into a variety of cosmetic formulations to enhance product versatility and appeal:
- Suitable for use in facial serums and creams- Compatible with eye contour formulations- Can be added to moisturizers and emulsions- Appropriate for inclusion in sheet masks- Utilized in leave-on skin treatments- Integrates well with gel-based products
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Creative Peptides is a trusted CDMO partner specializing in high-quality peptide synthesis, conjugation, and manufacturing under strict cGMP compliance. With advanced technology platforms and a team of experienced scientists, we deliver tailored peptide solutions to support drug discovery, clinical development, and cosmetic innovation worldwide.
From custom peptide synthesis to complex peptide-drug conjugates, we provide flexible, end-to-end services designed to accelerate timelines and ensure regulatory excellence. Our commitment to quality, reliability, and innovation has made us a preferred partner across the pharmaceutical, biotechnology, and personal care industries.