Abarelix
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CAT#
10-101-60
Chemical Structure
CAS No.
183552-38-7
Explanation
Abarelix is a synthetic decapeptide antagonist to gonadotropin releasing hormone (GnRH). It directly and competitively binds and blocks the gonadotropin releasing hormone receptors in the anterior pituitary, which inhibits the secretion and release of the luteinizing hormone (LH) and follicle stimulating hormone (FSH). For men, the inhibition of LH secretion prevents the release of testosterone. Therefore, it can relieve symptoms associated with prostate hypertrophy or prostate cancer.
Synonyms/Alias
Plenaxis;PPI-149;Abarelix;Abarelix-Depot-M;R-3827;R3827;R 3827
Molecular Formula
C72H95ClN14O14
M.W/Mr.
1416.086
Sequence
Three Letter Code: Ac-D-2-Nal-D-4-Cl-Phe-D-3-Pal-Ser-N-Me-Tyr-D-Asn-Leu-Lys(ipr)-Pro-D-Ala-NH2
Appearance
Solid powder
Technical Data
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