Anisomycin

Anisomycin is an antibiotic isolated from various Streptomyces species. It interferes with protein and DNA synthesis by inhibiting peptidyl transferase or the 80S ribosome system.

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CAT#Z10-101-164
CAS22862-76-6
Synonyms/AliasFlagecidin
M.F/FormulaC14H19NO4
M.W/Mr.265.31
Labeling Targetc-Jun N-terminal kinase (JNK)
ApplicationAnisomycin is used as a antineoplastic agent that inhibits or prevents the proliferation of neoplasms.
AppearanceSolid powder
Purity>98% (or refer to the Certificate of Analysis)
ActivityInhibitor
Biological ActivityAnisomycin is a potent protein synthesis inhibitor which interferes with protein and DNA synthesis by inhibiting peptidyl transferase or the 80S ribosome system. Anisomycin is a JNK activator, which increases phospho-JNK. Anisomycin is a bacterial antibiotic.
Areas of InterestImmunology & Inflammation
Cell Biology
Cancer
FunctionsAnisomycin is inactive against bacteria.
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