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Tetracosactide is a synthetic peptide, which corresponds to the first 24 amino acids of the naturally occurring hormone ACTH (adrenocorticotropic hormone). It stimulates the adrenal cortex to produce corticosteroids, mineralocorticoids, and, to a lesser extent, androgens.
| CAT# | 10-101-31 |
| Explanation | Sincalide corresponds to the C-terminal octapeptide of cholecystokinin (CCK) and acts on receptors within the gallbladder wall causing it to contract. |
| Synonyms/Alias | CCK-8; Cholecystokinin Octapeptide; (Des-Pyr1,Des-Gln2,Met5)-Caerulein |
| M.F/Formula | C49H62N10O16S3 |
| M.W/Mr. | 1143.3 |
| Sequence | Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2 |
| Labeling Target | Gastrin/cholecystokinin receptor |
| Application | Sincalide ammonium salt is used for the diagnosis of bile tract and pancreatic diseases, and for the clinical radiology of the intestinal tract. |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Biological Activity | Sincalide ammonium (Cholecystokinin octapeptide ammonium) is a rapid-acting amino acid polypeptide hormone analogue of cholecystokinin (CCK) for intravenous use in postevacuation cholecystography. Sincalide ammonium is an agent that promotes gallbladder contraction by injection and helps diagnose gallbladder and pancreas disorders. |
| Areas of Interest | Cardiovascular System & Diseases Pituitary & Hypothalamic Hormones |
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