Sincalide Ammonium Salt

Tetracosactide is a synthetic peptide, which corresponds to the first 24 amino acids of the naturally occurring hormone ACTH (adrenocorticotropic hormone). It stimulates the adrenal cortex to produce corticosteroids, mineralocorticoids, and, to a lesser extent, androgens.

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CAT#10-101-31
ExplanationSincalide corresponds to the C-terminal octapeptide of cholecystokinin (CCK) and acts on receptors within the gallbladder wall causing it to contract.
Synonyms/AliasCCK-8; Cholecystokinin Octapeptide; (Des-Pyr1,Des-Gln2,Met5)-Caerulein
M.F/FormulaC49H62N10O16S3
M.W/Mr.1143.3
SequenceAsp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2
Labeling TargetGastrin/cholecystokinin receptor
ApplicationSincalide ammonium salt is used for the diagnosis of bile tract and pancreatic diseases, and for the clinical radiology of the intestinal tract.
AppearanceSolid powder
Purity>98% (or refer to the Certificate of Analysis)
Biological ActivitySincalide ammonium (Cholecystokinin octapeptide ammonium) is a rapid-acting amino acid polypeptide hormone analogue of cholecystokinin (CCK) for intravenous use in postevacuation cholecystography. Sincalide ammonium is an agent that promotes gallbladder contraction by injection and helps diagnose gallbladder and pancreas disorders.
Areas of InterestCardiovascular System & Diseases
Pituitary & Hypothalamic Hormones
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