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Sincalide Ammonium Salt
CAT#
10-101-31
Synonyms/Alias
CCK-8; Cholecystokinin Octapeptide; (Des-Pyr1,Des-Gln2,Met5)-Caerulein
CAS No.
25126-32-3 (net)
Sequence
H-Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2 ammonium salt
M.W/Mr.
1143.3
Molecular Formula
C49H62N10O16S3
Source
Synthetic
Long-term Storage Conditions
−20°C
Application
Sincalide ammonium salt is used for the diagnosis of bile tract and pancreatic diseases, and for the clinical radiology of the intestinal tract.
Description
Sincalide corresponds to the C-terminal octapeptide of cholecystokinin (CCK) and acts on receptors within the gallbladder wall causing it to contract.
Areas of Interest
Hormonal therapy
Useful Tools
Sincalide corresponds to the C-terminal octapeptide of cholecystokinin (CCK) and acts on receptors within the gallbladder wall causing it to contract.
To establish normal gallbladder ejection fraction (GBEF) values for two sincalide (cholecystokinin [CCK]) infusion dose rates, 0.01 microg per kilogram of body weight infused for 3 minutes and 0.01 microg/kg infused for 60 minutes.
Ziessman, H. A., Muenz, L. R., Agarwal, A. K., & ZaZa, A. A. (2001). Normal values for sincalide cholescintigraphy: comparison of two methods. Radiology, 221(2), 404-410.
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