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Sincalide Ammonium Salt

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CAT#
10-101-31
Synonyms/Alias
CCK-8; Cholecystokinin Octapeptide; (Des-Pyr1,Des-Gln2,Met5)-Caerulein
CAS No.
25126-32-3 (net)
Sequence
H-Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2 ammonium salt
M.W/Mr.
1143.3
Molecular Formula
C49H62N10O16S3
Source
Synthetic
Long-term Storage Conditions
−20°C
Application
Sincalide ammonium salt is used for the diagnosis of bile tract and pancreatic diseases, and for the clinical radiology of the intestinal tract.
Description
Sincalide corresponds to the C-terminal octapeptide of cholecystokinin (CCK) and acts on receptors within the gallbladder wall causing it to contract.
Areas of Interest
Hormonal therapy
  • Background
  • Related Products
  • References

Sincalide corresponds to the C-terminal octapeptide of cholecystokinin (CCK) and acts on receptors within the gallbladder wall causing it to contract.

CAS: 38916-34-6 (net), 51110-01-1 (acetate)
Sequence: H-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH acetate salt (Disulfide bond)
M.W: 1637.88
Molecular Formula: C76H104N18O19S2
CAS: 75957-60-7 (net), 105184-37-0 (acetate)
Sequence: H-Arg-Lys-Glu-Val-Tyr-OH acetate salt
M.W: 813.89
Molecular Formula: C35H59N9O13
CAS: 103300-74-9
Sequence: (1-methyl-4,5-dihydroorotyl)- His-Pro-NH2
M.W: 477.46
Molecular Formula: C17H23N7O5
CAS: 16960-16-0
Sequence: H-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-OH acetate salt
M.W: 2933.5
Molecular Formula: C136H210N40O31S
CAS: 57773-63-4 (net), 124508-66-3 (pamoate salt)
Sequence: Pyr-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2 pamoate salt
M.W: 1744.96
Molecular Formula: C64H82N18O13

To establish normal gallbladder ejection fraction (GBEF) values for two sincalide (cholecystokinin [CCK]) infusion dose rates, 0.01 microg per kilogram of body weight infused for 3 minutes and 0.01 microg/kg infused for 60 minutes.

Ziessman, H. A., Muenz, L. R., Agarwal, A. K., & ZaZa, A. A. (2001). Normal values for sincalide cholescintigraphy: comparison of two methods. Radiology, 221(2), 404-410.

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