(D-Phe12)-Bombesin contains an aromatic D-residue that alters its folding, stability, and receptor affinity. The peptide is widely used to probe G-protein-coupled receptor pathways and ligand-motif recognition. Its modified structure enhances utility in studying neuropeptidergic activity across model systems. Investigators apply it in signaling pathway mapping and peptide analog development.
1. Cell-based adhesion assays for isolation of snake venom’s integrin antagonists
3. Adipose tissue is a key organ for the beneficial effects of GLP-2 metabolic function
4. C-Peptide replacement therapy and sensory nerve function in type 1 diabetic neuropathy
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