FC131

FC 131 is an antagonist of CXCR4 with anti-HIV activity

Online Inquiry

CAT#10-101-256
CAS606968-52-9
Synonyms/AliasCyclo[2-Nal-Gly-D-Tyr-Arg-Arg]
Chemical Namecyclo[3-(2-naphthalenyl)-L-alanylglycyl-D-tyrosyl-L-arginyl-L-arginyl]
M.F/FormulaC36H47N11O6
M.W/Mr.729.8
SequenceOne Letter Code: XGYRR (Modifications: Cyclic peptide, X = 2-Nal, Tyr-3 = D-Tyr] 
Three Letter Code: Nal-Gly-Tyr-Arg-Arg
Labeling TargetC-X-C chemokine receptor type 4 (CXCR4)
ApplicationCXCR4 antagonist (IC50 = 126 nM). Displays anti-HIV activity in assays using NL4-3 and IIIB strains (EC50 = 21 nM for both strains).
AppearanceCrystalline solid
Purity≥95%
ActivityAntagonist
Biological ActivityFC131 (cyclo (-D-Tyr-Arg-Arg-Nal-Gly-)) is a selective, cyclopentapeptide CXCR4 antagonist with IC50 of 126nM, exhibits anti-HIV activity in assays using NL4-3 and IIIB strains with EC50 of 21nM.
TargetCXCR
Quick Inquiry
×
If you have any peptide synthesis requirement in mind, please do not hesitate to contact us at . We will endeavor to provide highly satisfying products and services.
Customer Support & Price Inquiry

* Please kindly note that our products and services can only be used to support research purposes (Not for clinical use).

Creative Peptides has accumulated a huge library of peptide knowledge including frontier peptide articles, application of peptides, useful tools, and more!

 The peptide neuroprotectant Tat-NR2B9c, also known as NA-1, is a Tat peptide consisting of the nine C-terminal ...

  Delcasertib, also known as KAI-9803, is a 23-amino acid peptide and δ-protein kinase C (δ-PKC) inhibitor. KAI-9 ...

An overview of Palmitoyl pentapeptide-4  The potential of topical peptides to improve aging skin has been widely discussed in ...

 Elcatonin acetate, a physicochemically and biologically stable synthetic derivative of calcitonin transformed fr ...

 Nafarelin acetate is a gonadotropin-releasing hormone (GnRH) agonist which is as effective as danazol in the tre ...

Contact Us

USA

Address:

Tel: |

Email:

Germany

Address:

Copyright © 2024 Creative Peptides. All rights reserved.