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Heptapeptide

CAT#
CPC1641
Synonyms/Alias
Acetyl-Heptapeptide 4
Description
Heptapeptide-4 is a synthetic peptide composed of alanine, arginine, glutamic acid, glutamine and methionine. It smooths wrinkles through a mechanism similar to that of Botulinum toxin.
References
Snap-7; Total Age Repair 24K Red Ginseng Cream
INCIName
Heptapeptide-4
Storage
Common storage 2-8℃, long time storage -20℃.
Functions
Heptapeptide 4 helps balance the skin conditioning and nourishes the skin with a fine moist layer.

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Heptapeptide-4 is a synthetic peptide composed of alanine, arginine, glutamic acid, glutamine and methionine. It smooths wrinkles through a mechanism similar to that of Botulinum toxin.

A number of protein kinases have been implicated in the phosphorylation of the CTD during the transition from transcription initiation to elongation. Among these are the Cdk7 subunit of the GTF IIH (TFIIH) and the Cdk9 subunit of P-TEFb, a factor that regulates transcription elongation. The Cdk7 kinase phosphorylates serine 5 of the CTD heptapeptide motif. And, while the specificity of human P-TEFb remains controversial, a close yeast homologue of its Cdk9 subunit, Ctk1, modifies the serine residue at position 2 of the CTD heptapeptide repeat.

Mandal, S. S., Cho, H., Kim, S., Cabane, K., & Reinberg, D. (2002). FCP1, a phosphatase specific for the heptapeptide repeat of the largest subunit of RNA polymerase II, stimulates transcription elongation. Molecular and cellular biology, 22(21), 7543-7552.

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