Myelin Oligodendrocyte Glycoprotein (MOG) is a glycoprotein believed to be important in the process of myelinization of nerves in the central nervous system (CNS). It is a transmembrane protein expressed on the surface of oligodendrocyte cell and on the outermost surface of myelin sheaths.
CAT# | 10-101-57 |
CAS | 163913-87-9 |
Background | Myelin oligodendrocyte glycoprotein (MOG) 35-55 is a minor component of CNS myelin. Produces a relapsing-remitting neurological disease with extensive plaque-like demyelination, common to the manifestations of multiple sclerosis. Induces strong T and B cell responses and is highly encephalitogenic. |
Synonyms/Alias | MOG(35-55); MOG35-55; MOG 35-55; Myelin Oligodendrocyte Glycoprotein(35-55); Myelin Oligodendrocyte Glycoprotein35-55; Myelin Oligodendrocyte Glycoprotein 35-55 |
M.F/Formula | C118H177N35O29S |
M.W/Mr. | 2581.99 |
Sequence | Met-Glu-Val-Gly-Trp-Tyr-Arg-Ser-Pro-Phe-Ser-Arg-Val-Val-His-Leu -Tyr-Arg-Asn-Gly-Lys |
Labeling Target | T-cell and B-cell |
Application | Interest in MOG has centered on its role in demyelinating diseases, particularly multiple sclerosis (MS). |
Areas of Interest | Immunomodulating Agents Multiple Sclerosis |
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