Peptide YY (PYY) is a gut hormone which is primarily released from endocrine cells of the distal digestive tract in proportion to both the calorie content of a meal and its energy source composition.
CAT# | 10-101-97 |
CAS | 118997-30-1 (net) |
Background | Peptide YY (PYY) also known as peptide tyrosine tyrosine is a peptide that in humans is encoded by the PYY gene. Peptide YY is a short (36-amino acid) peptide released from cells in the ileum and colon in response to feeding. In the blood, gut, and other elements of periphery, PYY acts to reduce appetite; similarly, when injected directly into the central nervous system, PYY is also anorexigenic, i.e., it reduces appetite. Peptide YY can be produced as the result of enzymatic breakdown of crude fish proteins and ingested as a food product. |
Synonyms/Alias | PYY; Peptide YY; C16118 |
M.F/Formula | C194H295N55O57 |
M.W/Mr. | 4309.81 |
Sequence | H-Tyr-Pro-Ile-Lys-Pro-Glu-Ala-Pro-Gly-Glu-Asp-Ala-Ser-Pro-Glu-Glu-Leu-Asn-Arg-Tyr-Tyr-Ala-Ser-Leu-Arg-His-Tyr-Leu-Asn-Leu-Val-Thr-Arg-Gln-Arg-Tyr-NH₂ |
Labeling Target | Neuropeptide Y Receptor |
Application | Peptide YY (PYY) plays an important role in regulating gastrointestinal secretion and motility. |
Areas of Interest | Metabolic Disease Neurological Disease |
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