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Pramlintide

Pramlintide is an analogue of amylin, a small peptide hormone that is released into the bloodstream by the β-cells of the pancreas along with insulin, after a meal. Like insulin, amylin is completely absent in individuals with Type I diabetes.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: 10-101-28

CAS No:151126-32-8

Synonyms/Alias:AC 0137; AC 137; Symlin; Tripro-Amylin; riproamylin; Pramlintide; LS-181996; LS181996; Amylin

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M.F/Formula
C171H267N51O53S2
M.W/Mr.
3949.4
Sequence
Lys-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-His-Ser-Ser-Asn-Asn-Phe-Gly-Pro-Ile-Leu-Pro-Pro-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH2(Disulfide bridge cys2 and cys7)
Labeling Target
Amylin receptor
Application
Pramlintide (Symlin) has been approved by the FDA as a new injectable drug for diabetes (both type 1 and 2).
Activity
Agonist
Biological Activity
Pramlintide is a polypeptide analogue of human amylin. Pramlintide, an antidiabetic agent, is antineoplastic in colorectal cancer.
Areas of Interest
Metabolic Disease
Functions
Receptor activity
Target
Calcitonin receptor
Source#
Synthetic
Solubility
−20°C
Organism
Human
BoilingPoint
N/A
Melting Point
N/A

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