Vapreotide is a somatostatin analog with a higher metabolic stability than the parent hormone. Vapreotide reduces splanchnic blood flow, inhibits growth hormone release, and inhibits the release of peptides and vasoactive compounds from neuroendocrine tumors.
CAT No: 10-101-44
CAS No:103222-11-3 (net), 116430-60-5 (acetate) 849479-74-9(ChemIDplus)
Synonyms/Alias:Vapreotide acetate;116430-60-5;Docrised;OCTASTATIN ACETATE;RC-160 acetate;Vapreotide monoacetate;Octastatin;Sanvar;BMY-41606 acetate;Vapreotide acetate [MI];Vapreotide acetate [WHO-DD];5562377HFV;DP-05-094;acetic acid;(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-N-[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-19-[[(2R)-2-amino-3-phenylpropanoyl]amino]-16-[(4-hydroxyphenyl)methyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-7-propan-2-yl-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide;UNII-5562377HFV;Vapreotide acetate [USAN];849479-74-9;L-Tryptophanamide, D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-, cyclic (2->7)-disulfide, acetate (salt);L-Tryptophanamide, D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-, cyclic (2->7)-disulfide, monoacetate (salt);BMY-41606;Vapreotide acetate (USAN);RC-160;Docrised (mexico);Debio-8609;SCHEMBL294911;EX-A7487A;Vapreotide acetate [USAN:WHO-DD];G13841;Q27261277;D-Phenylalanyl-L-Cysteinyl-L-Tyrosyl-D-Tryptophyl-L-Lysyl-L-Valyl-L-Cysteinyl-L-Tryptophanamide Cyclic (2->7)-Disulphide Acetate Salt (1:N);L-Tryptophanamide, D-Phenylalanyl-L-Cysteinyl-L-Tyrosyl-D-Tryptophyl-L-Lysyl-L-Valyl-L-Cysteinyl-, Cyclic (2->7)-Disulfide, Acetate (1:N);
2. Autoinhibition and phosphorylation-induced activation of phospholipase C-γ isozymes
4. Store-operated Ca2+ entry sustains the fertilization Ca2+ signal in pig eggs
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