This peptide is derived from amino acid residues 57-68 of a9-gliadin and represents an immunodominant epitope that has been shown to elicit HLA-DQ2-restricted T-cell responses in celiac patients. This epitope is resistant to pancreatic proteolysis.
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M.W/Mr. | 1455.8 |
Sequence | One Letter Code: QLQPFPQPQLPY Three Letter Code: H-Gln-Leu-Gln-Pro-Phe-Pro-Gln-Pro-Gln-Leu-Pro-Tyr-OH |
References | 1. Arentz-Hansen, H. et al. J Exp Med 191, 603 (2000). 2. Hausch, F. et al. Am J Physiol Gastrointest Liver Physiol 283, 996 (2002). 3. Mamone, G. et al. J Chromatogr B 855, 236 (2007). |
1. Immune responses to homocitrulline-and citrulline-containing peptides in rheumatoid arthritis
4. TMEM16F and dynamins control expansive plasma membrane reservoirs
5. The spatiotemporal control of signalling and trafficking of the GLP-1R
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