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  5. Aquaporin-2 (254-267), pSER261, human

Aquaporin-2 (254-267), pSER261, human

This peptide is a fragment of the human aquaporin-2 (AQP2) phosphorylated at Ser261. Protein phosphorylation plays a key role in vasopressin signaling in renal-collecting duct. Phosphorylation at several AQP2 residues including Ser256 and Ser261, is altered in response to vasopressin. It is possible that both sites are involved in vasopressin-dependent AQP2 trafficking.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: O06018

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.W/Mr.
1713.8
Sequence
One Letter Code: RQSVELH-pS-PQSLPR
Three Letter Code: H-Arg-Gln-Ser-Val-Glu-Leu-His-pSer-Pro-Gln-Ser-Leu-Pro-Arg-OH
References
1. Nielsen, S. et al. PNAS 90, 11663 (1993);
2. Hoffert, J. et al. PNAS 103, 7159 (2006).

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