Micafungin sodium
Micafungin is an antifungal drug that belongs to the antifungal class of compounds known as echinocandins and exerts its effect by inhibiting the synthesis of 1,3-beta-D-glucan, an integral component of the fungal cell wall.
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| CAT# | Z10-101-158 |
| CAS | 208538-73-2 |
| Synonyms/Alias | Funguard, FK463 |
| M.F/Formula | C56H70N9O23SNa |
| M.W/Mr. | 1292.26 |
| Labeling Target | 1, 3-beta-D-glucan synthesis |
| Application | Formerly known as FK463, micafungin is a semisynthetic lipopeptide synthesized from a fermentation product of Coleophoma empetri that works as an antifungal agent. It is a glucan synthesis inhibitor of the echinocandin structural class. |
| Activity | Inhibitor |
| Biological Activity | Micafungin Sodium is the sodium salt form of micafungin, a semi-synthetic echinocandin derived from a natural product of the fungus Coleophoma empetri with antifungal activity. Micafungin, like other cyclic lipopeptides, noncompetitively inhibits the fungal specific enzyme 1,3-beta-D-glucan synthase, an enzyme essential for the synthesis of the important fungal cell wall component 1,3-beta-D-glucan. |
| Areas of Interest | Infection |
| Functions | 1,3-beta-d-glucan synthase activity |
| Disease | Candidiasis of the esophagus;
Disseminated candidiasis;
Candidal septicemia |
| Storage | −20°C |
Organism | Aspergillus niger (strain CBS 513.88 / FGSC A1513) |
BoilingPoint | N/A |
Melting Point | N/A |
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