Micafungin is an antifungal drug that belongs to the antifungal class of compounds known as echinocandins and exerts its effect by inhibiting the synthesis of 1,3-beta-D-glucan, an integral component of the fungal cell wall.
1, 3-beta-D-glucan synthesis
Formerly known as FK463, micafungin is a semisynthetic lipopeptide synthesized from a fermentation product of Coleophoma empetri that works as an antifungal agent. It is a glucan synthesis inhibitor of the echinocandin structural class.
Areas of Interest
1,3-beta-d-glucan synthase activity
Candidiasis of the esophagus; Disseminated candidiasis; Candidal septicemia
Aspergillus niger (strain CBS 513.88 / FGSC A1513)