MPS-Gαi3

Name: MPS-Gαi3
Brand: Creative Peptides
SKU: GR2159
Availability: MadeToOrder

MPS-Gαi3 is a potent inhibitor targeting the G protein subunit alpha i3. With its high affinity and selectivity, MPS-Gαi3 is extensively employed in biomedicine for studying GPCR-mediated signaling pathways. It plays a pivotal role in investigating diseases involving Gαi3, such as cardiovascular disorders, cancers, and neurological conditions, contributing to novel therapeutic interventions.

Please kindly note that our products and services can only be used to support research purposes (Not for clinical use).

CAT No: GR2159

CAS No: 439223-21-9

Chemical Name: (4S)-4-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S)-4-amino-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-aminopropanoyl]amino]propanoyl]amino]-3-methylbutanoyl]amino]propanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]pyrrolidine-2-carbonyl]amino]propanoyl]amino]-3-methylbutanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]propanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]propanoyl]amino]hexanoyl]amino]-4-oxobutanoyl]amino]-4-oxobutanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]amino]-5-[[(2R)-1-[[2-[[(2S)-1-[[(1S)-1-carboxy-2-(4-hydroxyphenyl)ethyl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-sulfanylpropan-2-yl]amino]-5-oxopentanoic acid

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Specification Technical Data Publications Customer reviews and Q&A

M.F/Formula	C120H205N29O31S
M.W/Mr.	2582.15
Sequence	H-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Lys-Asn-Asn-Leu-Lys-Glu-Cys-Gly-Leu-Tyr-OH

InChI	InChI=1S/C120H205N29O31S/c1-57(2)44-78(109(168)145-88(120(179)180)52-73-35-37-74(150)38-36-73)132-93(153)55-126-103(162)89(56-181)146-106(165)77(39-40-94(154)155)135-104(163)76(33-28-30-42-122)134-110(169)83(49-62(11)12)140-114(173)86(54-92(125)152)142-115(174)85(53-91(124)151)141-105(164)75(32-27-29-41-121)133-98(157)68(22)128-107(166)79(45-58(3)4)138-111(170)81(47-60(7)8)136-99(158)69(23)129-108(167)80(46-59(5)6)139-112(171)84(50-63(13)14)143-118(177)96(66(19)20)148-102(161)72(26)130-116(175)90-34-31-43-149(90)119(178)87(51-64(15)16)144-113(172)82(48-61(9)10)137-100(159)70(24)131-117(176)95(65(17)18)147-101(160)71(25)127-97(156)67(21)123/h35-38,57-72,75-90,95-96,150,181H,27-34,39-56,121-123H2,1-26H3,(H2,124,151)(H2,125,152)(H,126,162)(H,127,156)(H,128,166)(H,129,167)(H,130,175)(H,131,176)(H,132,153)(H,133,157)(H,134,169)(H,135,163)(H,136,158)(H,137,159)(H,138,170)(H,139,171)(H,140,173)(H,141,164)(H,142,174)(H,143,177)(H,144,172)(H,145,168)(H,146,165)(H,147,160)(H,148,161)(H,154,155)(H,179,180)/t67-,68-,69-,70-,71-,72-,75-,76-,77-,78-,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,95-,96-/m0/s1
InChI Key	PASXXILKKBWILJ-WEIPZPPTSA-N
Canonical SMILES	CC(C)CC(C(=O)NC(CC1=CC=C(C=C1)O)C(=O)O)NC(=O)CNC(=O)C(CS)NC(=O)C(CCC(=O)O)NC(=O)C(CCCCN)NC(=O)C(CC(C)C)NC(=O)C(CC(=O)N)NC(=O)C(CC(=O)N)NC(=O)C(CCCCN)NC(=O)C(C)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(C(C)C)NC(=O)C(C)NC(=O)C2CCCN2C(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(C(C)C)NC(=O)C(C)NC(=O)C(C)N
Isomeric SMILES	C[C@@H](C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CS)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC2=CC=C(C=C2)O)C(=O)O)N

1. Application of human liver organoids as a patient-derived primary model for HBV infection and related hepatocellular carcinoma

2. Olfactory receptor based piezoelectric biosensors for detection of alcohols related to food safety applications

3. Spatiotemporal delivery of nanoformulated liraglutide for cardiac regeneration after myocardial infarction

4. GLP-1, exendin-4 and C-peptide regulate pancreatic islet microcirculation, insulin secretion and glucose tolerance in rats

5. Extended exenatide administration enhances lipid metabolism and exacerbates pancreatic injury in mice on a high fat, high carbohydrate diet

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