RGDS

RGDS is a classic adhesion motif interacting with integrin receptors and influencing cell-matrix communication. The short sequence promotes studies of β-turn formation, surface binding, and ligand-receptor docking. Researchers use it to probe extracellular-matrix interactions and receptor specificity. Its simplicity supports widespread biochemical and structural analyses.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
RGDS(CAS 91037-65-9)

CAT No: R1883

CAS No:91037-65-9

Synonyms/Alias:Arg-gly-asp-ser;91037-65-9;Rgds peptide;Fibronectin tetrapeptide;Arginyl-glycyl-aspartyl-serine;RGDS;UNII-AC6UDA2MFC;L-Arginylglycyl-L-alpha-aspartyl-L-serine;AC6UDA2MFC;MFCD00076452;CHEMBL265628;(3S)-3-[[2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]acetyl]amino]-4-[[(1S)-1-carboxy-2-hydroxyethyl]amino]-4-oxobutanoic acid;L-Serine, N-(N-(N-L-arginylglycyl)-L-alpha-aspartyl)-;RGDS peptide; Fibronectin tetrapeptide;Arg-Gly-Asp-Ser?;Fibronectin Inhibitor;Arg-Gly-Asp-Ser peptide;H-Arg-Gly-Asp-Ser-OH;L-Serine, L-arginylglycyl-L-alpha-aspartyl-;SCHEMBL7394659;DTXSID50920002;Fibronectin Inhibitor Tetrapeptide;CHEBI:232857;NNRFRJQMBSBXGO-CIUDSAMLSA-N;BDBM50241180;DU-728;RGDS peptide;Fibronectin tetrapeptide;AKOS024457642;Arg-Gly-Asp-Ser, >=95% (HPLC);CS-3266;FR73590;NCGC00167153-01;(6S,12S,15S)-1,6-diamino-12-(carboxymethyl)-15-(hydroxymethyl)-1-imino-7,10,13-trioxo-2,8,11,14-tetraazahexadecan-16-oic acid;AS-56630;DA-61200;HY-12290;C77102;BRD-K08859203-001-01-9;L-SERINE, L-ARGINYLGLYCYL-L-.ALPHA.-ASPARTYL-;Q27273860;(3S)-3-{2-[(2S)-2-AMINO-5-CARBAMIMIDAMIDOPENTANAMIDO]ACETAMIDO}-3-{[(1S)-1-CARBOXY-2-HYDROXYETHYL]CARBAMOYL}PROPANOIC ACID;(6S,12S,15S)-1,6-diamino-12-(carboxymethyl)-16-hydroxy-1-imino-7,10,13-trioxo-2,8,11,14-tetraazahexadecane-15-carboxylic acid;(S)-3-[2-((S)-2-Amino-5-guanidino-pentanoylamino)-acetylamino]-N-((R)-1-carboxy-2-hydroxy-ethyl)-succinamic acid;(S)-3-[2-((S)-2-Amino-5-guanidino-pentanoylamino)-acetylamino]-N-((S)-1-carboxy-2-hydroxy-ethyl)-succinamic acid;2-[1-[1-amino-4-amino(imino)methylamino-(1S)-butylcarboxamidomethylcarboxamido]-2-carboxy-(1S)-ethylcarboxamido]-3-hydroxy-(2S)-propanoic acid;2-{1-[1-amino-4-amino(imino)methylaminobutylcarboxamidomethylcarboxamido]-2-carboxyethylcarboxamido}-3-hydroxypropanoic acid;3-({2-[(2-Amino-5-carbamimidamido-1-hydroxypentylidene)amino]-1-hydroxyethylidene}amino)-4-[(1-carboxy-2-hydroxyethyl)imino]-4-hydroxybutanoic acid;3-[(S)-2-((S)-2-Amino-5-guanidino-pentanoylamino)-acetylamino]-N-(1-carboxy-2-hydroxy-ethyl)-succinamic acid;3-[2-((S)-2-Amino-5-guanidino-pentanoylamino)-acetylamino]-N-((S)-1-carboxy-2-hydroxy-ethyl)-succinamic acid;3-[2-(2-Amino-5-guanidino-pentanoylamino)-acetylamino]-N-(1-carboxy-2-hydroxy-ethyl)-succinamic acid;3-[2-(2-Amino-5-guanidino-pentanoylamino)-acetylamino]-N-(1-carboxy-2-hydroxy-ethyl)-succinamic acid (RGDS);

Chemical Name:(3S)-3-[[2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]acetyl]amino]-4-[[(1S)-1-carboxy-2-hydroxyethyl]amino]-4-oxobutanoic acid

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C15H27N7O8
M.W/Mr.
433.42
Sequence
One Letter Code:RGDS
Three Letter Code:H-Arg-Gly-Asp-Ser-OH
Shipping Condition
RT, or blue ice upon request.
InChI
InChI=1S/C15H27N7O8/c16-7(2-1-3-19-15(17)18)12(27)20-5-10(24)21-8(4-11(25)26)13(28)22-9(6-23)14(29)30/h7-9,23H,1-6,16H2,(H,20,27)(H,21,24)(H,22,28)(H,25,26)(H,29,30)(H4,17,18,19)/t7-,8-,9-/m0/s1
InChI Key
NNRFRJQMBSBXGO-CIUDSAMLSA-N
Canonical SMILES
C(CC(C(=O)NCC(=O)NC(CC(=O)O)C(=O)NC(CO)C(=O)O)N)CN=C(N)N
Isomeric SMILES
C(C[C@@H](C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CO)C(=O)O)N)CN=C(N)N

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