Substance P Acetate
The undecapeptide substance P has a number of peripheral actions which include contraction of smooth muscle, reduction of blood pressure and stimulation of secretory tissues. Substance P also occurs in neurones in the central nervous system. It is of particular interest as a possible neurotransmitter or neuromodulator, released by primary sensory neurones.
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| CAT# | 10-101-52 |
| CAS | 33507-63-0 (net) |
| Synonyms/Alias | Euler-Gaddum Substance P; Hypothalamic Substance P; SP(1-11); SP1-11; SP 1-11; SP |
| M.F/Formula | C63H98N18O13S |
| M.W/Mr. | 1347.63 |
| Sequence | H-Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2 |
| Labeling Target | Neurokinin Receptor |
| Application | Substance P is a modulator of pain transmission. As an extremely potent vasodilator, it produces significant bronchodilation in normal and asthmatic subjects and a maximal increase in forearm blood flow. |
| Activity | Modulator |
| Areas of Interest | Neurological Disease |
| Target | Neurokinin Receptor |
| Source# | Synthetic |
Long-term Storage Conditions | −20°C |
BoilingPoint | N/A |
Melting Point | N/A |
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