Tetracosactide Acetate
Tetracosactide is a synthetic peptide, which corresponds to the first 24 amino acids of the naturally occurring hormone ACTH (adrenocorticotropic hormone). It stimulates the adrenal cortex to produce corticosteroids, mineralocorticoids, and, to a lesser extent, androgens.
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| CAT# | 10-101-01 |
| Chemical Structure |  |
| CAS | 16960-16-0 |
| Synonyms/Alias | Cosyntropin; Tetracosactrin; α1-24-Corticotropin; ACTH(1-24); 1-24-ACTH; 1-24-Corticotropin; ACTH 1-24; ACTH1-24; Cortosyn; Cortrosyn; Tetracosactide; Tetracosapeptide; ACTH (1-24); Tetracosactid; Tetracosactide; Cortrosinta; Actholain; Cortrosyn; Synacthen; Nuvacthen depot; Cortrophin S |
| M.F/Formula | C136H210N40O31S |
| M.W/Mr. | 2933.5 |
| Sequence | One Letter Code: SYSMEHFRWGKPVGKKRRPVKVYP
Three Letter Code: H-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-OH |
| Application | Tetracosactide is used for diagnostic purposes. It is suitable for treatment of adrenal insufficiency of central origin. It can also be used to diagnose Addison's disease. |
| Activity | Agonist |
| Target | Adrenocorticotropic hormone receptor |
| Storage | Desiccate at -20°C |
Solubility | H2O : 100 mg/mL (34.09 mM; Need ultrasonic) |
Shipping Condition | Room temperature in continental US; may vary elsewhere. |
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