Thyrotropin-Releasing Hormone (TRH), Free Acid

Thyrotropin-releasing hormone (TRH) is an endogenous tripeptide that acts as a neurotransmitter and neurohormone. TRH regulates hypothalamic-pituitary-adrenal (HPA) and estrogenic signaling pathways. TRH exhibits immunomodulatory and neuroprotective activities. TRH prevents oxidative stress, caspase-mediated apoptosis, glutamate toxicity, and neuroinflammation. Additionally, TRH stimulates epidermal regeneration in ex vivo models, increasing would healing. TRH activates the TRH receptor.

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Synonyms/AliasTRH | Thyroliberin | Thyrotropin-releasing hormone | Prothyroliberin
SequenceOne Letter Code: Pyr-HP
Three Letter Code: Pyr-His-Pro
AppearanceWhite or off-white lyophilized powder
Purity> 95%
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