Receptor for advanced glycation end products (RAGE) antagonist. Blocks S100P, S100A4 and HMGB-1 mediated RAGE activation in vitro and in vivo. Inhibits growth and metastasis of rat glioma tumors. Reduces cell growth and RAGE-mediated NF-κB activity in human PDAC cell lines. Inhibits effects of TDI exposure in BALB/c mice.
CAT# | R0852 |
CAS | 1092460-91-7 |
M.F/Formula | C57H101N13O17S |
M.W/Mr. | 1272.56 |
Sequence | Ac-ELKVLMEKEL-NH2 |
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