Hexapeptide-9 is a synthetic peptide containing Glutamine, Glycine and Proline residues.

1. Emu oil in combination with other active ingredients for treating skin imperfections

2. SERS spectrum of the peptide thymosin‐β4 obtained with Ag nanorod substrate

3. Quantitative Analysis of Ligands Effects on Bioefficacy of Nanoemulsion encapsulating Depigmenting Active

4. Crystal Structure of BamB from Pseudomonas aeruginosa and Functional Evaluation of Its Conserved Structural Features

For example, linear hexapeptide 9 was prepared by removing the –Troc protection on 3 to afford 7 and appending the glycine-pyrrole side chain 5 to give 8. After -Fmoc removal, coupling to 4 afforded the desired branched hexapeptide 9, with only the final cyclization and protection group removal remaining. However, compound 9 proved highly unstable and did not succumb to cyclization.

Curzon, S. S., Garcia, J. M., & Konopelski, J. P. (2015). Total synthesis of nominal cyclocinamide B and investigation into the identity of the cyclocinamides. Tetrahedron letters, 56(23), 2991-2994.