Met-Enkephalin

Met-enkephalin is a 5-amino acid endogenous peptide that acts as an agonist at opioid receptors. It is one of the first discovered endogenous opioid peptides, or opiopeptins, along with its congener, Leu-enkephalin.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
Met-Enkephalin(CAS 58569-55-4)

CAT No: R1822

CAS No:58569-55-4

Synonyms/Alias:MET-enkephalin;58569-55-4;H-Tyr-Gly-Gly-Phe-Met-OH;Methionine enkephalin;Tyr-Gly-Gly-Phe-Met-OH;METENKEFALIN;TYR-GLY-GLY-PHE-MET;(Met5)-enkephalin;Metenkefalin [INN];[Met]enkephalin;[5-Methionine]Enkephalin;Opioid growth factor;ENKEPHALIN, METHIONINE;[Met5]-ENKEPHALIN;9JEZ9OD3AS;Porcine beta-endorphin 1-5;Sh-pentapeptide-19;CCRIS 4225;EINECS 261-335-8;(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylsulfanylbutanoic acid;1-5-Adrenorphin (human);Met-Enkephalin acetate salt;NSC 374896;opioid growth factor (OGF);Enkephalin-(5-l-methionine);CHEMBL13786;METENKEFALIN [WHO-DD];CHEBI:6618;DTXSID80332078;NSC-374896;MFCD00076415;[Met5]Enkephalin acetate salt hydrate;Metenkephalin;(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenyl-propanoyl]amino]-4-methylsulfanyl-butanoic acid;L-Methionine, L-tyrosylglycylglycyl-L-phenylalanyl-;Met Enkephalin;methionine-enkephalin;Adrenorphin (human), 6-de-L-arginine-7-de-L-arginine-8-de-L-valinamide-;(Met(5))enkephalin;[Met(5)]enkephalin;L-TYROSYLGLYCYLGLYCYL-L-PHENYLALANYL-L-METHIONINE .BETA.-ENDORPHIN HUMAN-(1-5)-PEPTIDE;(Met(5))-enkephalin;[Met(5)]-enkephalin;(2S,5S,14S)-14-Amino-5-benzyl-15-(4-hydroxyphenyl)-2-(2-(methylthio)ethyl)-4,7,10,13-tetraoxo-3,6,9,12-tetraazapentadecan-1-oic acid;M-ENK;Met(5)-Enkephalin;5 Methionine Enkephalin;5-Methionine Enkephalin;82362-17-2;Enkephalin, 5-Methionine;UNII-9JEZ9OD3AS;L-Tyr-Gly-Gly-L-Phe-L-Met;met-enkefalin;H-L-Tyr-Gly-Gly-L-Phe-L-Met-OH;Met5-Enkephalin;NP2 Enkephalin;[Met]-enkephalin;Met-Enk;1-5 Adrenorphin;(2S)-2-(((2S)-2-((2-((2-(((2S)-2-amino-3-(4-hydroxyphenyl)propanoyl)amino)acetyl)amino)acetyl)amino)-3-phenyl-propanoyl)amino)-4-methylsulfanyl-butanoic acid;(2S)-2-(((2S)-2-((2-((2-(((2S)-2-amino-3-(4-hydroxyphenyl)propanoyl)amino)acetyl)amino)acetyl)amino)-3-phenylpropanoyl)amino)-4-methylsulfanylbutanoic acid;(2S)-2-(((2S)-2-((2-((2-(((2S)-2-azaniumyl-3-(4-hydroxyphenyl)propanoyl)amino)acetyl)amino)acetyl)amino)-3-phenylpropanoyl)amino)-4-methylsulfanylbutanoate;(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-azaniumyl-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylsulfanylbutanoate;L-Tyrosylglycylglycyl-L-phenylalanyl-L-methionine;Inno-105;SCHEMBL632433;GTPL1614;DTXCID80283172;IRT-101;HY-P0073;SH-PENTAPEPTIDE-19 [INCI];BDBM50019056;AKOS030525639;CS-5426;DB12668;NCGC00163683-01;AS-58159;DA-75437;FM108776;H-Tyr-Gly-Gly-Phe-Met-OH; H-YGGFM-OH;NS00054117;C75740;Met-Enkephalin (H-L-Tyr-Gly-Gly-L-Phe-L-Met-OH);N-(N-(N-(N-L-Tyrosylglycyl)glycyl)-L-phenylalanyl)-L-methionine;L-TYROSYLGLYCYLGLYCYL-L-PHENYLALANYL-L-METHIONINE BETA-ENDORPHIN HUMAN-(1-5)-PEPTIDE;([Met]-enkephalin)2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methylsulfanyl-butyric acid([Met]-enkephalin;(S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methylsulfanyl-butyric acid;1632987-92-8;2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-1-oxo-3-phenyl-propylamino]-4-methylsulfanyl-butyric acid;2-[1-[1-amino-2-(4-hydroxyphenyl)-(1S)-ethylcarboxamidomethylcarboxamidomethylcarboxamido]-2-phenyl-(1S)-ethylcarboxamido]-4-methylsulfanyl-(2S)-butanoic acid;2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methylsulfanyl-butyric acid;261-335-8;

Custom Peptide Synthesis
cGMP Peptide
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  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C27H35N5O7S
M.W/Mr.
573.7
Sequence
One Letter Code:YGGFM
Three Letter Code:H-Tyr-Gly-Gly-Phe-Met-OH
Appearance
White or off-white lyophilized powder
Purity
≥98%
Long-term Storage Conditions
DMSO : ≥ 40 mg/mL (69.73 mM)

H2O : 6.67 mg/mL (11.63 mM; Need ultrasonic)
InChI
InChI=1S/C27H35N5O7S/c1-40-12-11-21(27(38)39)32-26(37)22(14-17-5-3-2-4-6-17)31-24(35)16-29-23(34)15-30-25(36)20(28)13-18-7-9-19(33)10-8-18/h2-10,20-22,33H,11-16,28H2,1H3,(H,29,34)(H,30,36)(H,31,35)(H,32,37)(H,38,39)/t20-,21-,22-/m0/s1
InChI Key
YFGBQHOOROIVKG-FKBYEOEOSA-N

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