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[SER140]-PLP(139-151)

[SER140]-PLP(139-151) is a fragment of myelin proteolipid protein, induce experimental autoimmune encephalomyelitis (EAE).

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
[SER140]-PLP(139-151)(CAS 122018-58-0)

CAT No: R1135

CAS No:122018-58-0

Synonyms/Alias:122018-58-0;Proteolipid protein (139-151);[SER140]-PLP(139-151);PLP(139-151)TFA;AKOS024457171;NCGC00167265-01;DA-56936;SER140-PLP(139-151)?;CAS 122018-58-0;G78392;

Chemical Name:(S,Z)-3-((Z)-(((S)-1-((2S,3Z,6Z,8S,9Z,11S,12Z,14S,15Z,18Z,20S,21Z,23S,24Z,26S)-2-((1H-imidazol-5-yl)methyl)-11-((1H-indol-3-yl)methyl)-26-amino-14-(4-aminobutyl)-4,7,10,13,16,19,22,25-octahydroxy-23-(hydroxymethyl)-27-(1H-imidazol-5-yl)-8,20-diisobutyl-3

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cGMP Peptide
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  • CMC information required for an IND
  • IND and NDA support
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M.F/Formula
C72H104N20O17
M.W/Mr.
1521.7
Sequence
One Letter Code:HSLGKWLGHPDKF
Three Letter Code:H-His-Ser-Leu-Gly-Lys-Trp-Leu-Gly-His-Pro-Asp-Lys-Phe-OH
Purity
≥97% (HPLC)
Length
13
Long-term Storage Conditions
Soluble to 2 mg/ml in water
Shipping Condition
Ship with RT , or blue ice upon request
InChI
InChI=1S/C72H104N20O17/c1-40(2)25-51(63(99)80-36-60(95)84-55(30-45-34-77-39-82-45)71(107)92-24-14-21-58(92)70(106)89-54(31-61(96)97)68(104)85-50(20-11-13-23-74)66(102)90-56(72(108)109)27-42-15-6-5-7-16-42)86-67(103)53(28-43-32-78-48-18-9-8-17-46(43)48)88-65(101)49(19-10-12-22-73)83-59(94)35-79-64(100)52(26-41(3)4)87-69(105)57(37-93)91-62(98)47(75)29-44-33-76-38-81-44/h5-9,15-18,32-34,38-41,47,49-58,78,93H,10-14,19-31,35-37,73-75H2,1-4H3,(H,76,81)(H,77,82)(H,79,100)(H,80,99)(H,83,94)(H,84,95)(H,85,104)(H,86,103)(H,87,105)(H,88,101)(H,89,106)(H,90,102)(H,91,98)(H,96,97)(H,108,109)/t47-,49-,50-,51-,52-,53-,54-,55-,56-,57-,58-/m0/s1
InChI Key
UQIBUOXNUPHALR-UVIWMAFZSA-N
Canonical SMILES
[H]N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CC1=CNC=N1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=CC=C1)C(O)=O

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