Argifin

Argifin, an esteemed biomedical innovation, is a pharmacotherapeutic marvel meticulously designed for the efficacious amelioration of various intricate cardiovascular ailments. Within its composition lies the veritable elixir of arginine, an innate amino acid proficient in stimulating the augmentation of nitric oxide concentrations within the corporeal establishment. Consequently, this preeminent phenomenon impeccably fosters vasodilation, culminating in optimized hemodynamic dynamics, and the abatement of perilously elevated arterial tension.

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CAT No: R2081

CAS No: 243975-37-3

Synonyms/Alias: Argifin;243975-37-3;CHEMBL197199;(2R,5S,8S,11S,15S)-5-[3-[[amino-(methylcarbamoylamino)methylidene]amino]propyl]-8-benzyl-2,7-dimethyl-3,6,9,13,17-pentaoxo-1,4,7,10,14-pentazacycloheptadecane-11,15-dicarboxylic acid;DTXSID00332297;(2R,5S,8S,11S,15S)-5-(3-((amino-(methylcarbamoylamino)methylidene)amino)propyl)-8-benzyl-2,7-dimethyl-3,6,9,13,17-pentaoxo-1,4,7,10,14-pentazacycloheptadecane-11,15-dicarboxylic acid;1w9v;1wb0;BDBM10853;DTXCID40283390;FTD 0668;HY-P2274;BDBM50173286;DB03632;CS-0121055;NS00071704;(2R,5S,8S,11S,15S)-8-benzyl-2,7-dimethyl-5-[3-({[(methylcarbamoyl)amino]methanimidoyl}amino)propyl]-3,6,9,13,17-pentaoxo-1,4,7,10,14-pentaazacycloheptadecane-11,15-dicarboxylic acid;5-[3-[amino-(methylcarbamoylamino)methylidene]aminopropyl]-8-benzyl-2,7-dimethyl-3,6,9,13,17-pentaoxo-1,4,7,10,14-pentazacycloheptadecane-11,15-dicarboxylic acid;Cyclo[D-alanyl-N5-[imino[[(methylamino)carbonyl]amino]methyl]-L-ornithyl-N-methyl-L-phenylalanyl-L-beta-aspartyl-L-beta-aspartyl] (9CI);

Chemical Name: (2R,5S,8S,11S,15S)-5-[3-[[amino-(methylcarbamoylamino)methylidene]amino]propyl]-8-benzyl-2,7-dimethyl-3,6,9,13,17-pentaoxo-1,4,7,10,14-pentazacycloheptadecane-11,15-dicarboxylic acid

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Specification Technical Data Publications Customer reviews and Q&A

M.F/Formula	C29H41N9O10
M.W/Mr.	675.7
Sequence	Three Letter Code:D-N(1)Ala-Arg(CONHMe)(CONHMe)-N(Me)Phe-Asp(2)-OH.N(2)Asp(1)-OH

InChI	InChI=1S/C29H41N9O10/c1-15-23(41)35-17(10-7-11-32-28(30)37-29(48)31-2)25(43)38(3)20(12-16-8-5-4-6-9-16)24(42)36-19(27(46)47)14-22(40)34-18(26(44)45)13-21(39)33-15/h4-6,8-9,15,17-20H,7,10-14H2,1-3H3,(H,33,39)(H,34,40)(H,35,41)(H,36,42)(H,44,45)(H,46,47)(H4,30,31,32,37,48)/t15-,17+,18+,19+,20+/m1/s1
InChI Key	UHBHXSDKGLPPGO-HTDHLNIYSA-N
Canonical SMILES	CC1C(=O)NC(C(=O)N(C(C(=O)NC(CC(=O)NC(CC(=O)N1)C(=O)O)C(=O)O)CC2=CC=CC=C2)C)CCCN=C(N)NC(=O)NC
Isomeric SMILES	C[C@@H]1C(=O)N[C@H](C(=O)N([C@H](C(=O)N[C@@H](CC(=O)N[C@@H](CC(=O)N1)C(=O)O)C(=O)O)CC2=CC=CC=C2)C)CCCN=C(N)NC(=O)NC

1. Emerging applications of nanotechnology for diagnosis and therapy of disease: a review

2. Oleic acid and glucose regulate glucagon-like peptide 1 receptor expression in a rat pancreatic ductal cell line

4. Low bone turnover and low BMD in Down syndrome: effect of intermittent PTH treatment

5. Uncarboxylated osteocalcin decreases insulin-stimulated glucose uptake without affecting insulin signaling and regulators of mitochondrial biogenesis in myotubes

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Argifin

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