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Argifin

Argifin, an esteemed biomedical innovation, is a pharmacotherapeutic marvel meticulously designed for the efficacious amelioration of various intricate cardiovascular ailments. Within its composition lies the veritable elixir of arginine, an innate amino acid proficient in stimulating the augmentation of nitric oxide concentrations within the corporeal establishment. Consequently, this preeminent phenomenon impeccably fosters vasodilation, culminating in optimized hemodynamic dynamics, and the abatement of perilously elevated arterial tension.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: R2081

CAS No:243975-37-3

Synonyms/Alias:Argifin;243975-37-3;CHEMBL197199;(2R,5S,8S,11S,15S)-5-[3-[[amino-(methylcarbamoylamino)methylidene]amino]propyl]-8-benzyl-2,7-dimethyl-3,6,9,13,17-pentaoxo-1,4,7,10,14-pentazacycloheptadecane-11,15-dicarboxylic acid;DTXSID00332297;(2R,5S,8S,11S,15S)-5-(3-((amino-(methylcarbamoylamino)methylidene)amino)propyl)-8-benzyl-2,7-dimethyl-3,6,9,13,17-pentaoxo-1,4,7,10,14-pentazacycloheptadecane-11,15-dicarboxylic acid;1w9v;1wb0;BDBM10853;DTXCID40283390;FTD 0668;HY-P2274;BDBM50173286;DB03632;CS-0121055;NS00071704;(2R,5S,8S,11S,15S)-8-benzyl-2,7-dimethyl-5-[3-({[(methylcarbamoyl)amino]methanimidoyl}amino)propyl]-3,6,9,13,17-pentaoxo-1,4,7,10,14-pentaazacycloheptadecane-11,15-dicarboxylic acid;5-[3-[amino-(methylcarbamoylamino)methylidene]aminopropyl]-8-benzyl-2,7-dimethyl-3,6,9,13,17-pentaoxo-1,4,7,10,14-pentazacycloheptadecane-11,15-dicarboxylic acid;Cyclo[D-alanyl-N5-[imino[[(methylamino)carbonyl]amino]methyl]-L-ornithyl-N-methyl-L-phenylalanyl-L-beta-aspartyl-L-beta-aspartyl] (9CI);

Chemical Name:(2R,5S,8S,11S,15S)-5-[3-[[amino-(methylcarbamoylamino)methylidene]amino]propyl]-8-benzyl-2,7-dimethyl-3,6,9,13,17-pentaoxo-1,4,7,10,14-pentazacycloheptadecane-11,15-dicarboxylic acid

Custom Peptide Synthesis
cGMP Peptide
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M.F/Formula
C29H41N9O10
M.W/Mr.
675.7
Sequence
Three Letter Code:D-N(1)Ala-Arg(CONHMe)(CONHMe)-N(Me)Phe-Asp(2)-OH.N(2)Asp(1)-OH
InChI
InChI=1S/C29H41N9O10/c1-15-23(41)35-17(10-7-11-32-28(30)37-29(48)31-2)25(43)38(3)20(12-16-8-5-4-6-9-16)24(42)36-19(27(46)47)14-22(40)34-18(26(44)45)13-21(39)33-15/h4-6,8-9,15,17-20H,7,10-14H2,1-3H3,(H,33,39)(H,34,40)(H,35,41)(H,36,42)(H,44,45)(H,46,47)(H4,30,31,32,37,48)/t15-,17+,18+,19+,20+/m1/s1
InChI Key
UHBHXSDKGLPPGO-HTDHLNIYSA-N
Canonical SMILES
CC1C(=O)NC(C(=O)N(C(C(=O)NC(CC(=O)NC(CC(=O)N1)C(=O)O)C(=O)O)CC2=CC=CC=C2)C)CCCN=C(N)NC(=O)NC
Isomeric SMILES
C[C@@H]1C(=O)N[C@H](C(=O)N([C@H](C(=O)N[C@@H](CC(=O)N[C@@H](CC(=O)N1)C(=O)O)C(=O)O)CC2=CC=CC=C2)C)CCCN=C(N)NC(=O)NC

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