Asp-Phe

Tetracosactide is a synthetic peptide, which corresponds to the first 24 amino acids of the naturally occurring hormone ACTH (adrenocorticotropic hormone). It stimulates the adrenal cortex to produce corticosteroids, mineralocorticoids, and, to a lesser extent, androgens.

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CAT#10-101-305
ExplanationL-Aspartyl-L-phenylalanine is a dipeptide inhibitor of angiotensin-converting enzyme (ACE) and a metabolite of the synthetic non-caloric sweetener aspartame. It is formed from aspartame by intestinal intracellular esterases. L-Aspartyl-L-phenylalanine inhibits ACE with a Ki value of 11 µM for the rabbit enzyme. Serum levels of L-aspartyl-L-phenylalanine are positively associated with pancreatic ductal adenocarcinoma.
Chemical Name(3S)-3-amino-4-[[(1S)-1-carboxy-2-phenylethyl]amino]-4-oxobutanoic acid
M.F/FormulaC13H16N2O5
M.W/Mr.280.28
SequenceOne Letter Code: DF
Three Letter Code: L-Asp-L-phe
Purity>98 %
ActivityInhibitor
TargetAngiotensin-converting Enzyme (ACE)
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