Asp-Phe

Name: Asp-Phe
Brand: Creative Peptides
SKU: 10-101-305
Availability: MadeToOrder

L-Aspartyl-L-phenylalanine is a dipeptide inhibitor of angiotensin-converting enzyme (ACE) and a metabolite of the synthetic non-caloric sweetener aspartame. It is formed from aspartame by intestinal intracellular esterases. L-Aspartyl-L-phenylalanine inhibits ACE with a Ki value of 11 µM for the rabbit enzyme. Serum levels of L-aspartyl-L-phenylalanine are positively associated with pancreatic ductal adenocarcinoma.

Please kindly note that our products and services can only be used to support research purposes (Not for clinical use).

CAT No: 10-101-305

CAS No: 13433-09-5

Synonyms/Alias: L-Aspartyl-L-phenylalanine;13433-09-5;H-ASP-PHE-OH;ASP-PHE;Aspartyl-phenylalanine;Aspartylphenylalanine;Demethylaspartame;l-a-aspartyl-l-phenylalanine;CHEBI:73830;L-alpha-Aspartyl-L-phenylalanine;(S)-3-Amino-4-(((S)-1-carboxy-2-phenylethyl)amino)-4-oxobutanoic acid;a-Aspartylphenylalanine;alpha-L-Aspartyl-L-phenylalanine;EINECS 236-557-3;(3S)-3-amino-4-[[(1S)-1-carboxy-2-phenylethyl]amino]-4-oxobutanoic acid;a-L-Aspartyl-L-phenylalanine;N-L-aspartyl-L-PhenylAlanine;CHEMBL170376;N-L-a-aspartyl-L-PhenylAlanine;N-L-alpha-aspartyl-L-PhenylAlanine;alpha-Aspartylphenylalanine;3-amino-N-(carboxyphenethyl)-Succinamic acid stereoisomer;3.Aspartame acid;3-amino-N-(a-carboxyphenethyl)-Succinamic acid stereoisomer;(S)-3-amino-4-((S)-1-carboxy-2-phenylethylamino)-4-oxobutanoic acid;MFCD00063155;.alpha.L-Aspartyl-L-phenylalanine;DF dipeptide;(3S)-3-amino-4-(((1S)-1-carboxy-2-phenylethyl)amino)-4-oxobutanoic acid;L-Aspartyl-L-phenylalanine; Aspartame Imp. B (EP); Aspartame Impurity B;alpha-Asp-Phe;D-F Dipeptide;L-a-Asp-L-phe;L-alpha-Asp-L-Phe;L-Asp-L-Phe;N-L-alpha-Aspartyl-3-phenyl-L-alanine;N-Aspartylphenylalanine;Asp-Phe, 96%;N-alpha-Aspartylphenylalanine;SCHEMBL135366;alphaL-Aspartyl-L-phenylalanine;N-L-alpha-Aspartylphenylalanine;Aspartate Phenylalanine dipeptide;Aspartate-Phenylalanine dipeptide;DTXSID20928570;YZQCXOFQZKCETR-UWVGGRQHSA-N;n-alpha-l-aspartyl-l-phenylalanine;13433-09-5 (free amine);Aspartic acid phenylalanine dipeptide;Aspartic acid-phenylalanine dipeptide;BDBM50049759;MSK001019;AKOS022180930;AS-46818;FA108005;1ST001019;CS-0044366;NS00014795;L-alpha-Aspartyl-L-phenylalanine Hydrochloride;F10617;N-L-alpha-Aspartyl-L-phenylalanine Hydrochloride;Q27144148;

Chemical Name: (3S)-3-amino-4-[[(1S)-1-carboxy-2-phenylethyl]amino]-4-oxobutanoic acid

Quick Inquiry Custom Peptide Synthesis

Thymopentin Acetate

Thymopentin, also known as TP-5, is a synthetic derivative of thymopoietin, a thymic hormone, and has immunoregulatory properties. Thymopentin interacts with T cells, reduces endocrine and behavioral responses to experimental stress. It is also found to increase the number of cells undergoing apoptosis in irradiated cells and selectively bind to apoptotic cells.

Inquiry
Deslorelin Acetate

Deslorelin acetate is an injectable gonadotropin releasing hormone super-agonist (GnRH agonist) also known as an LHRH agonist. It stops the production of sex hormones (testosterone and oestrogen).

Inquiry
Carperitide

Atrial Natriuretic Peptide (ANP) (1-28), human, porcine is a 28-amino acid hormone, that is normally produced and secreted by the human heart in response to cardiac injury and mechanical stretch. ANP (1-28) inhibits endothelin-1 secretion in a dose-dependent way.

Inquiry
Carbetocin

Carbetocin is a long-acting synthetic agonist analogue of human oxytocin, with antihemorrhagic and uterotonic activities. Upon administration, carbetocin targets, binds to and activates peripheral oxytocin receptors that are present on the smooth musculature of the uterus. This causes uterus contractions and prevents excessive bleeding after childbirth, particularly following Cesarean section, and may be used to decrease blood loss during hysteroscopic myomectomy.

Inquiry
Gonadorelin Acetate

Gonadorelin is a trophic peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released from GnRH neurons within the hypothalamus. The peptide belongs to gonadotropin-releasing hormone family. It constitutes the initial step in the hypothalamic–pituitary–gonadal axis.

Inquiry
Somatostatin

Somatostatin is a tetradecapeptide which can suppress the growth hormone (GH) secretion and control the pituitary hormone secretion in human CNS.

Inquiry
Thymosin β4 Acetate

Thymosin β4 is a 43 amino acid peptide which is regarded as the main intracellular G-actin sequestering peptide. Extracellular thymosin β4 may contribute to physiological processes such as angiogenesis, wound healing and regulation of inflammation.

Inquiry
Terlipressin

Terlipressin is a synthetic triglycyllysine derivative of vasopressin with vasoconstrictive, antihemorrhagic, and antidiuretic properties. Upon intravenous administration, terlipressin, an inactive prodrug, is biotransformed to its active moiety, lysine vasopressin (LVP), a nonselective vasopressin analogue with affinity for vasopressin receptors V1 (V1a), V2 and V3 (V1b). As a V1 agonist, terlipressin increases systemic vascular resistance, particularly in the splanchnic area, resulting in a decrease of portal pressure. V1 binding also promotes platelet aggregation and glycogenolysis, while V3 binding induces adrenocorticotropic hormone (ACTH) secretion. Compared to vasopressin, terlipressin has a minimal effect on V2 receptors, which are responsible for promotion of water reabsorption in the collecting ducts of the kidney via stimulation of cyclic AMP production.

Inquiry
DOTA-cyclo(RGDfK) acetate

Inquiry
Aviptadil Acetate

Aviptadil, also known as vasoactive intestinal polypeptide (VIP), is a 28 amino acid neuropeptide that belongs to the glucagon-growth hormone-releasing factor secretion superfamily. Aviptadil acts as a potent systemic vasodilator and bronchodilator. It inhibits the proliferation of vascular and bronchial smooth muscle cells and decreases platelet aggregation. These biological effects are mediated by specific VIP receptors.

Inquiry

M.F/Formula	C13H16N2O5
M.W/Mr.	280.28
Sequence	One Letter Code:DF Three Letter Code:H-Asp-Phe-OH
Purity	>98 %
Activity	Inhibitor
Target	Angiotensin-converting Enzyme (ACE)

Shipping Condition	+20°C (International: -20°C)
InChI	InChI=1S/C13H16N2O5/c14-9(7-11(16)17)12(18)15-10(13(19)20)6-8-4-2-1-3-5-8/h1-5,9-10H,6-7,14H2,(H,15,18)(H,16,17)(H,19,20)/t9-,10-/m0/s1
InChI Key	YZQCXOFQZKCETR-UWVGGRQHSA-N
Canonical SMILES	C1=CC=C(C=C1)CC(C(=O)O)NC(=O)C(CC(=O)O)N
Isomeric SMILES	C1=CC=C(C=C1)C[C@@H](C(=O)O)NC(=O)[C@H](CC(=O)O)N