Dynorphin A-( 1- 17) is an endogenous opioid derived from the prohormone prodynorphin. It acts as endogenous κ-agonist that is resistant to enzymatic degradation. And it is a neuroactive peptide with potent analgesic effects.
CAT# | 10-101-81 |
CAS | 80448-90-4 |
Synonyms/Alias | Dynorphin (1-17); Dynorphin(1-17); Dynorphin 1-17; Dynorphin1-17; Dynorphins; Dynorphin A (1-17); Dynorphin A 1-17; Dynorphin A1-17; DynorphinA 1-17; DynorphinA1-17; DynorphinA(1-17); D004399; LS-185865; LS185865; LS 185865;L-tyrosyl-glycyl-glycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-arginyl-L-isoleucyl-L-arginyl-L-prolyl-L-lysyl-L-leucyl-L-lysyl-L-tryptophyl-L-alpha-aspartyl-L-asparagyl-L-glutamine |
Chemical Name | (2S)-5-amino-2-[[(2S)-4-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-methylpentanoyl]amino]-5-carbamimidamidopentanoyl]pyrrolidine-2-carbonyl]amino]hexanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-carboxypropanoyl]amino]-4-oxobutanoyl]amino]-5-oxopentanoic acid |
M.F/Formula | C99H155N31O23 |
M.W/Mr. | 2147.48 |
Sequence | One Letter Code: YGGFLRRIRPKLKWDNQ Three Letter Code: H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln-OH |
Labeling Target | Opioid receptor |
Application | Dynorphin A-(1- 17) is an endogenous opioid peptide that has been implicated in the pathophysiology of both traumatic brain injury (TBI) and spinal cord injury (SCI). |
Purity | ≥95% |
Areas of Interest | Neurological Disease |
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