L-NMMA acetate is a nitric oxide synthase inhibitor of all NOS isoforms, like NOS1, NOS2, and NOS3.
CAT# | 10-101-117 |
CAS | 17035-90-4 (net), 53308-83-1 (acetate) |
Background | L-NMMA is the archetypal competitive NOS inhibitor to which other inhibitors are often compared. It is a relatively non-selective inhibitor of all NOS isoforms. The Ki values for nNOS (rat), eNOS (human), and iNOS (mouse) are approximately 0.18, 0.4, and 6 µM, respectively. >> Read More |
Synonyms/Alias | Tilarginine Acetate; Targinine Acetate |
M.F/Formula | C9H20N4O4 |
M.W/Mr. | 248.28 |
Sequence | H-Arg(Me)-OH acetate salt |
Labeling Target | Tilarginine |
Application | L-NMMA is a useful clinical tool as NO synthase inhibitor to study the role and the effects of NO in cardiovascular and gastrointestinal disorders, hypertension, septic shock, inflammation, infection, stroke and neurodegenerative disorders. |
Activity | Inhibitor |
Areas of Interest | Cardiovascular Disease |
Target | NO Synthase |
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