Trimetazidine Dihydrochloride

Trimetazidine Dihydrochloride is a 3-ketoacyl-coenzyme, a thiolase inhibitor. It is a cellular antiischemic agent indicated in the management and prophylaxis of angina pectoris.

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CAT#10-101-126
CAS5011-34-7 (net), 13171-25-0 (dihydrochloride)
Synonyms/Alias1-(2,3,4-Trimethoxybenzyl)piperazine · 2 HCl
M.F/FormulaC14H24N2O3
M.W/Mr.268.35
Labeling Target3-ketoacyl-CoA thiolase, peroxisomal
ApplicationTrimetazidine is an anti-ischemic (anti-anginal) metabolic agent, which improves myocardial glucose utilization through inhibition of fatty acid metabolism, also known as fatty acid oxidation inhibitor.
ActivityInhibitor
Biological ActivityTrimetazidine dihydrochloride is a kind of drug for treatment of chronic ischemic disorders. It improves myocardial glucose utilization through inhibition of fatty acid metabolism, known as fatty acid oxidation inhibitor.
Areas of InterestCardiovascular Disease
FunctionsPalmitoyl-coa oxidase activity
DiseaseAngina pectoris
TargetFatty Acid Oxidation
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