Econazole Sulfosalicylate
Econazole Sulfosalicylate
Econazole Sulfosalicylate is an antifungal agent applied topically or intravaginally. Econazole, an imidazole derivative, is indicated in the treatment of skin infections such as dermatophytosis, superficial candidasis, and tinea versicolor, and of infections of the nails. Econazole is also used as a topical antimycotic in veterinary medicine.
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| CAT# | 10-101-116 |
| CAS | 27220-47-9 (net), 118308-71-7 (sulfosalicylate) |
| Synonyms/Alias | 1-[2-[(4-Chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole sulfosalicylate; SQ-13050 sulfosalicylate; 1-[2,4-Dichloro-β-(4-chlorobenzyloxy)phenethyl]-imidazole sulfosalicylate |
| Chemical Name | 1-[2-[(4-chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]imidazole;2-hydroxy-5-sulfobenzoic acid |
| M.F/Formula | C18H15Cl3N2O.C7H6O6S |
| M.W/Mr. | 599.87 |
| Labeling Target | Lanosterol 14-alpha demethylase
Nuclear receptor subfamily 1 group I member 2 |
| Application | For the treatment of skin infections such as dermatophytosis, superficial candidasis, and tinea versicolor, and of infections of the nails. |
| Activity | Antagonist |
| Areas of Interest | Infection
Veterinary medicine |
| Disease | Tinea pedis; Candidiasis of skin; Pityriasis versicolor; Tinea corporis |
| Source# | Synthetic |
Organism | Human |
InChI | InChI=1S/C18H15Cl3N2O.C7H6O6S/c19-14-3-1-13(2-4-14)11-24-18(10-23-8-7-22-12-23)16-6-5-15(20)9-17(16)21;8-6-2-1-4(14(11,12)13)3-5(6)7(9)10/h1-9,12,18H,10-11H2;1-3,8H,(H,9,10)(H,11,12,13) |
InChI Key | WJRNYYWHDHVDCF-UHFFFAOYSA-N |
Canonical SMILES | C1=CC(=CC=C1COC(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl)Cl.C1=CC(=C(C=C1S(=O)(=O)O)C(=O)O)O |
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