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The gut hormone peptide YY (3-36) is a 36-amino acid peptide secreted from L-cells in the intestinal mucosa of the ileum and large intestine in proportion to caloric intake.
| CAT# | 10-101-96 |
| CAS | 123583-37-9 (net) |
| Synonyms/Alias | PYY (3-36); Peptide YY; C16118; PYY3-36 |
| M.F/Formula | C180H279N53O54 |
| M.W/Mr. | 4049.52 |
| Sequence | Ile-Lys-Pro-Glu-Ala-Pro-Gly-Glu-Asp-Ala-Ser-Pro-Glu-Glu-Leu-Asn-Arg-Tyr-Tyr-Ala-Ser-Leu-Arg-His-Tyr-Leu-Asn-Leu-Val-Thr-Arg-Gln-Arg-Tyr-NH2 |
| Labeling Target | Neuropeptide Y Receptor |
| Application | PYY (3-36) plays an important role in the regulation of appetite control. It is assumed that this effect is mediated through Y2 receptors in the hypothalamic arcuate nucleus (ARC), a brain area responsible for the regulation of food intake. PYY (3-36) may represent a promising tool for the treatment of obesity. |
| Areas of Interest | Metabolic Disease |
| Disease | Obesity |
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