PAR-2 (6-1) amide (human)

Tetracosactide is a synthetic peptide, which corresponds to the first 24 amino acids of the naturally occurring hormone ACTH (adrenocorticotropic hormone). It stimulates the adrenal cortex to produce corticosteroids, mineralocorticoids, and, to a lesser extent, androgens.

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Chemical Structure
ExplanationVKGILS-NH2 is a reversed amino acid sequence control peptide for SLIGKV-NH2 (protease-activated receptor 2 (PAR2) agonist). VKGILS-NH2 has no effect on DNA synthesis in cells.
Synonyms/Aliasretro-PAR-2 (1-6) amide (human), retro-SLIGKVamide, Thrombin Receptor-Like 1 (6-1) amide (human), Proteinase Activated Receptor 2 (6-1) amide (human), VKGILSamide, Coagulation Factor II Receptor-Like 1 (6-1) amide (human)
SequenceOne Letter Code: SLIGKV-NH₂
Three Letter Code: H-Ser-Leu-Ile-Gly-Lys-Val-NH₂ trifluoroacetate salt
Biological ActivityReversed amino acid sequence control peptide for SLIGKV-NH2, a protease-activated receptor 2 (PAR2) agonist.
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