Peginesatide
Peginesatide is a synthetic peptide attached to polyethylene glycol for the treatment of anemia. The polyethylene glycol moiety helps make the drug less immunogenic and prolongs its plasma half-life. Chemically, peginesatide is designed to mimic the pharmacological activity of erythropoietin, but is not a replica of the structure itself. Peginesatide consists of two 21-amino acid chains that are covalently bonded by a linker derived from iminodiacetic acid and β-alanine.
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| CAT# | 10-101-162 |
| CAS | 913976-27-9, 910576-32-8 |
| Synonyms/Alias | AF37702;AF 37702;Hematide;HSDB 8181;Peginesatide;UNII-JX56W9N61Q |
| M.F/Formula | C233H352N62O60S6 |
| M.W/Mr. | 5174.06 |
| Labeling Target | Erythropoietin receptor |
| Application | Treatment of anemia associated with chronic kidney disease |
| Activity | Stimulator |
| Biological Activity | Peginesatide is a synthetic peptide attached to polyethylene glycol for the treatment of anemia. The polyethylene glycol moiety helps make the drug less immunogenic and prolongs its plasma half-life. |
| Areas of Interest | Chronic kidney disease |
| Functions | Identical protein binding |
| Disease | Anemia in chronic kidney disease |
| Source# | Synthetic |
Storage | -20°C |
Organism | Human |
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