Peginesatide

Peginesatide is a synthetic peptide attached to polyethylene glycol for the treatment of anemia. The polyethylene glycol moiety helps make the drug less immunogenic and prolongs its plasma half-life. Chemically, peginesatide is designed to mimic the pharmacological activity of erythropoietin, but is not a replica of the structure itself. Peginesatide consists of two 21-amino acid chains that are covalently bonded by a linker derived from iminodiacetic acid and β-alanine.

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CAT#10-101-162
CAS913976-27-9, 910576-32-8
Synonyms/AliasAF37702;AF 37702;Hematide;HSDB 8181;Peginesatide;UNII-JX56W9N61Q
M.F/FormulaC233H352N62O60S6
M.W/Mr.5174.06
Labeling TargetErythropoietin receptor
ApplicationTreatment of anemia associated with chronic kidney disease
ActivityStimulator
Biological ActivityPeginesatide is a synthetic peptide attached to polyethylene glycol for the treatment of anemia. The polyethylene glycol moiety helps make the drug less immunogenic and prolongs its plasma half-life.
Areas of InterestChronic kidney disease
FunctionsIdentical protein binding
DiseaseAnemia in chronic kidney disease
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