AF37702;AF 37702;Hematide;HSDB 8181;Peginesatide;UNII-JX56W9N61Q
Treatment of anemia associated with chronic kidney disease
Peginesatide is a synthetic peptide attached to polyethylene glycol for the treatment of anemia. The polyethylene glycol moiety helps make the drug less immunogenic and prolongs its plasma half-life. Chemically, peginesatide is designed to mimic the pharmacological activity of erythropoietin, but is not a replica of the structure itself. Peginesatide consists of two 21-amino acid chains that are covalently bonded by a linker derived from iminodiacetic acid and β-alanine.
Areas of Interest
Chronic kidney disease