Our company specializes in peptide-based drug research alongside development and production. Our clients worldwide benefit from our peptide dosage form screening services which combine in-depth technical knowledge with extensive industry experience. Our expert team applies sophisticated analytical methods and cutting-edge screening processes to assess various peptide formulations which include injectables, lyophilized powders, oral forms, and both conventional and novel delivery systems.
We apply a multifaceted screening method for dosage forms that evaluates chemical stability alongside bioavailability and release characteristics. The chosen formulation achieves therapeutic objectives while meeting practical requirements such as scalable production methods and cost-effective manufacturing. Our partnership enables clients to optimize development schedules while reducing research risks and advancing from laboratory breakthroughs to market introduction.
We evaluate suitable dosage forms—such as injectables, oral formulations, transdermal systems, inhalation therapies, and nasal sprays—based on the physicochemical properties of peptides, including molecular weight, solubility, and stability. Our recommendations are tailored to guide formulation development in the most appropriate direction.
By considering therapeutic objectives, administration routes, and target sites of action, we identify the optimal formulation strategy. For example, in emergency scenarios requiring rapid onset, we prioritize options like injectables or inhalation-based delivery.
We conduct detailed feasibility studies to assess the practicality of selected dosage forms. These include evaluations of process compatibility, equipment suitability, and raw material compatibility to ensure seamless production under current manufacturing conditions. Through lab-scale trials, we assess solubility, stability, and drug release characteristics across formulations to validate their feasibility, optimize rational design, and identify potential issues early in development.
Depending on the dosage form requirements, we screen and select appropriate excipients such as fillers, binders, disintegrants, solubilizers, and antioxidants.
We conduct compatibility studies between peptides and excipients using methods like accelerated stability testing and thermal analysis to ensure peptide integrity and avoid degradation or impurity formation caused by adverse interactions.
Based on selected dosage forms and excipients, we design and refine formulation processes—for example, sterilization and lyophilization for injectables, or granulation and tableting for oral forms. We optimize critical process parameters such as temperature, pressure, and processing time to improve product yield, consistency, and long-term stability, ensuring final formulations meet clinical and regulatory standards.
We develop tailored analytical methods for different peptide formulations, utilizing techniques such as HPLC, mass spectrometry (MS), infrared spectroscopy (IR), and particle size analysis.
Comprehensive quality evaluations—including content determination, purity analysis, related substance profiling, and dissolution/release testing—ensure formulation consistency and performance throughout the development cycle.
We perform extensive stability studies in accordance with international regulatory guidelines, including stress testing, accelerated aging, and long-term storage evaluation, to determine shelf life and storage conditions for peptide formulations.
We offer fully customized formulation development based on client-specific needs. This includes the design of novel delivery systems, sustained-release or long-acting formulations, and targeted delivery platforms, all aimed at enhancing therapeutic efficacy and safety.
We evaluate peptide solubility and stability in various solvent systems—such as aqueous solutions, buffers, and additive-containing formulations (e.g., with antioxidants or preservatives).
By determining the ideal pH range and examining physicochemical properties like clarity, solubility, and viscosity at different concentrations, we define the most effective composition for liquid formulations.
We explore a variety of solid dosage forms, including lyophilized powders for injection, spray-dried powders, tablets, and capsules. Compatibility testing with excipients (e.g., fillers, lubricants, disintegrants) helps identify optimal combinations.
We also assess the impact of different processing methods—like lyophilization, spray drying, and compression—on peptide activity, stability, and release profiles to select the best formulation pathway.
For injectable peptides, we assess solvent options (e.g., water for injection, saline, glucose solutions) and determine suitable injectable formats such as aqueous solutions or lyophilized powders.
We evaluate solubility, stability, and compatibility to ensure safety and efficacy. Packaging compatibility (e.g., with glass ampoules or pre-filled syringes) is also examined to avoid potential quality risks.
We explore advanced sustained and controlled-release systems such as microspheres, liposomes, and nanoparticles. Material screening focuses on identifying carriers that offer high drug loading, encapsulation efficiency, and controlled-release capabilities.
In vitro release studies help us optimize parameters to achieve desired release profiles, extending peptide activity in vivo and reducing dosing frequency.
Expert Team and Advanced Facilities
Our experienced R&D team includes specialists in medicinal chemistry, pharmaceutics, and biopharmaceutics. With deep knowledge of peptide properties and behavior, they accurately identify key formulation factors. Supported by state-of-the-art labs for synthesis, purification, analysis, and development, we deliver efficient and reliable screening services.
Tailored Screening Strategies
We create customized screening plans based on each client’s unique needs, considering the peptide’s structure, intended use, and clinical goals. From design to scale-up, we stay in close contact with clients to ensure the final formulation performs well in real-world applications.
Extensive Formulation Library
Our ever-growing library includes a wide range of peptide dosage forms—from injectables and controlled-release systems to transdermal, inhalation, and oral formulations. We evaluate each option for stability, absorption, release profile, and user convenience to help clients choose the best formulation with strong clinical and market potential.
Streamlined Screening Process
We use high-throughput tools and computer-aided design to speed up formulation development. Our streamlined workflow—from sample prep to testing—reduces development time and helps bring products to market faster.
Strict Quality Control
We apply rigorous quality control at every step, from raw materials to finished products. Our comprehensive QC system ensures consistent, high-quality results throughout the screening process.
We begin by discussing the drug's target use, administration route, expected effect, and basic peptide properties, while confirming the project scope, timeline, and responsibilities.
We analyze the peptide's solubility, stability, and other key properties, and predict its ADME profile to guide dosage form selection.
Based on peptide characteristics and project goals, we shortlist suitable formulations and evaluate their feasibility and compatibility.
We optimize the manufacturing process for selected formulations and prepare small-scale samples for testing.
Samples undergo thorough quality testing, and the best-performing 1-2 formulations are selected based on key performance metrics.
All results are summarized in a report, and formulations can be further refined based on client feedback and specific needs.
Yes. Once the best formulation has been established we provide ongoing technical support that addresses client-specific requirements. Our support extends beyond but includes assistance with clinical trial sample preparation and additional manufacturing process optimization and resolution of production formulation problems.
No. The peptide formulation screening services we offer are suitable for every kind of peptide including therapeutic peptide drugs and diagnostic peptide reagents. Our formulation screening services are customized to fit the unique traits of any peptide regardless of its length or production method.
