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Peptide Sequence Design

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

Improve Peptide StabilityAccelerate Peptide DiscoveryNext-Generation Peptide Design

As a leading innovator in custom peptide engineering, we offer end-to-end Peptide Sequence Design Services powered by computational analysis, structural prediction, and decades of biochemical expertise. Whether you need a therapeutic peptide, a functional research peptide, a targeting peptide, or a peptide for diagnostics, our team delivers high-precision, biologically validated, and synthesis-ready sequences tailored to your specific application. We combine AI-driven design tools, rational molecular engineering, and industry-grade synthesis capabilities to help you accelerate development and reduce R&D costs.

What Problems Our Peptide Sequence Design Can Solve

Our service is designed to address the most common and challenging issues in peptide research and product development, including:

Applicaiton of Peptide Sequence Design

  • Difficulty discovering high-performing peptide candidates: We use in-silico prediction, molecular modeling, and sequence optimization to rapidly identify peptides with high binding affinity, improved selectivity, or defined biological activity.
  • Poor peptide stability, solubility, or bioavailability: By optimizing amino-acid composition, charge, hydrophobicity, and structural conformation, we enhance peptide stability, protease resistance, and delivery efficiency.
  • Low success rate in peptide synthesis or purification: Our experts design sequences that avoid synthesis bottlenecks such as aggregation-prone regions, steric hindrance, or challenging motifs—resulting in higher yield and purity.
  • Lack of internal expertise or time to perform peptide optimization: We provide full technical support from design to synthesis, freeing your R&D team from repetitive iteration cycles.
  • Need for customized peptides for therapeutic, diagnostic, or research applications: From bioactive peptides and antimicrobial peptides to cell-penetrating peptides and epitope peptides, we help you design molecules tailored to your scientific goal.

Our Peptide Sequence Design Services

Custom Peptide Sequence Design

  • Tailored de novo design for therapeutic, functional, and targeting peptides
  • AI-assisted sequence prediction for higher binding affinity and improved selectivity
  • Structural modeling using secondary/tertiary structure prediction tools
  • Optimization of physicochemical properties (charge, hydrophobicity, length, solubility)

Peptide Optimization & Engineering

  • Rational design to enhance peptide stability, half-life, and protease resistance
  • Activity-driven engineering based on SAR (Structure-Activity Relationship) data
  • Sequence refinement to improve cell penetration, receptor interaction, or antimicrobial efficacy
  • Removal of synthesis bottlenecks to reduce aggregation and improve purity

Peptide Modification Strategy Design

  • Cyclization, stapling, and conformational locking for structural stability
  • PEGylation, lipidation, glycosylation, acetylation, amidation, and other functional modifications
  • Site-specific labeling for fluorescence, biotin, enzyme tags, or carrier proteins
  • Customized conjugation strategies for drug delivery or diagnostic applications

Peptide Library Design

  • High-diversity libraries for hit discovery and early-stage screening
  • Epitope mapping libraries for antibody development and vaccine research
  • Truncation, mutation, and alanine-scanning libraries for mechanistic studies
  • Sequence-focused mini-libraries optimized around a specific biological target

Synthesis-Ready Technical Package

  • Final optimized peptide sequence with full rationale
  • Physicochemical property prediction (solubility, stability, hydrophobicity index)
  • Structural modeling output and modification recommendations
  • Synthesis feasibility assessment with purification strategy guidance
  • Storage, handling, and downstream application suggestions

Optional Add-Ons

  • Custom peptide synthesis (research-grade to GMP-grade)
  • Advanced analytical testing (HPLC, MS, LC-MS/MS)
  • In vitro biological evaluation upon request

Key Benefits of Our Peptide Sequence Design

High Precision

Our design workflow integrates AI prediction and structural modeling to deliver highly accurate, function-driven peptide sequences.

Scientific Rigor

Each sequence is engineered using rational molecular design principles and validated through multi-parameter computational analysis.

Application-Oriented Design

Every peptide is customized for your specific research goal—therapeutic, diagnostic, or functional—ensuring maximum performance in real applications.

Enhanced Stability & Activity

We optimize charge distribution, hydrophobicity, and conformational structure to significantly improve biological activity and protease resistance.

Synthesis Feasibility Optimization

Our experts eliminate aggregation-prone motifs and synthesis bottlenecks, increasing yield, purity, and overall manufacturability.

Fast Turnaround

Streamlined workflows and automated modeling pipelines ensure quick delivery without compromising technical quality.

Full Technical Support

From early design to final synthesis, our team provides continuous scientific guidance, troubleshooting, and application recommendations.

Scalable Solutions

Our designs support all development stages—from research-grade peptides to full GMP production—matching the scale of your project.

From Concept to Sequence: Our Design Process

1

Requirement Consultation & Project Definition

We begin by understanding your target, application scenario, biological goals, and technical requirements to ensure every design decision aligns with your project strategy.

2

In-Depth Analysis & Design Strategy Planning

Our scientists evaluate known peptide structures, activity data, and target interactions, then create a customized design roadmap tailored to your research or product objectives.

3

AI-Enhanced Sequence Design & Structural Modeling

Using computational modeling, AI prediction tools, and rational engineering principles, we generate optimized peptide sequences with improved activity, stability, and synthetic feasibility.

4

Sequence Optimization & Modification Planning

We refine the sequence for solubility, bioavailability, conformational stability, and synthesis efficiency, while proposing the most effective modification or conjugation strategies.

5

Feasibility Review & Technical Validation

Each final design undergoes synthesis-ready evaluation, including structural prediction, physicochemical property assessment, and purification strategy recommendations.

6

Delivery of Complete Technical Package

You receive a comprehensive design report that includes optimized sequences, modeling data, modification suggestions, and synthesis guidelines ready for downstream work.

Peptide Sequence Design Use Cases

Therapeutic Peptide Development

  • Lead discovery: Identify novel peptide candidates with high affinity for disease-related targets.
  • Activity enhancement: Optimize therapeutic peptides for greater potency or receptor selectivity.
  • Stability improvement: Engineer peptides with extended half-life and improved protease resistance.
  • Drug delivery: Design targeting peptides and cell-penetrating peptides (CPPs) for controlled delivery systems.

Diagnostic & Biomarker Peptides

  • Assay development: Create optimized peptides for ELISA, immunoassays, or mass spectrometry controls.
  • Epitope peptides: Design predicted epitopes for antibody production or immunogenicity testing.
  • Imaging probes: Engineer fluorescent or biotin-labeled peptides for diagnostic platforms.

Vaccine & Immunotherapy Research

  • Epitope mapping: Identify B-cell and T-cell epitopes for vaccine antigen development.
  • Neoantigen peptide design: Generate personalized epitopes for cancer immunotherapy.
  • Peptide adjuvants: Engineer short immune-modulating peptides to enhance vaccine response.

Functional & Bioactive Peptide Development

  • Anti-microbial peptides: Design peptides with improved antimicrobial spectrum and stability.
  • Metabolic regulation peptides: Develop peptides for antioxidant, anti-inflammatory, or metabolic applications.
  • Nutraceutical peptides: Create sequences optimized for food and supplement product formulations.

Protein Research & Structural Biology

  • Protein interaction mapping: Design peptides to probe protein-protein interactions.
  • Structural mimetics: Generate peptide fragments that mimic structural motifs in larger proteins.
  • Enzyme substrate design: Create synthetic peptide substrates for kinetic or mechanistic studies.

Peptide Libraries for Screening

  • Hit discovery libraries: Develop high-diversity peptide sets for activity screening.
  • SAR optimization libraries: Design systematic variants for structure–activity analysis.
  • Mutation & truncation panels: Explore functional residues with alanine scanning or positional mutation.

Biotechnology & Industrial Applications

  • Affinity purification ligands: Engineer peptides with high-selectivity binding for chromatography.
  • Material science: Create peptides for surface coating, biomaterial binding, or nanostructure assembly.
  • Biosensors: Design peptides as recognition elements for sensor platforms.

Start Your Project Today — Fast, Professional, and Accurate

We provide high-precision peptide sequence design built around the specific goals of your research or product development. Using advanced computational modeling, AI-driven prediction, and expert molecular engineering, we create peptide sequences that deliver superior stability, activity, and synthesis success. Whether you're developing therapeutic peptides, functional peptides, diagnostic tools, or research reagents, our team ensures every sequence is optimized, validated, and fully ready for downstream applications. Contact us now to discuss your projects.

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