O-(1,1-Dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-alpha-methyl-L-tyrosine

This tyrosine analog includes tert-butyl ether protection and α-methyl substitution that restricts backbone mobility. Researchers employ it to manipulate aromatic environment, steric constraints, and conformational bias. Its dual protections provide precise synthetic control. The residue is valuable in stabilized peptide frameworks.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
O-(1,1-Dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-alpha-methyl-L-tyrosine(CAS 1309873-74-2)

CAT No: R2117

CAS No:1309873-74-2

Synonyms/Alias:1309873-74-2;Fmoc-|A-Me-Tyr(tBu)-OH;N-Fmoc-a-methyl-4-tert-butoxy-L-phenylalanine;O-(1,1-Dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-alpha-methyl-L-tyrosine;(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(tert-butoxy)phenyl)-2-methylpropanoic acid;(S)-2-Fmoc-amino-3-(4-(tert-butoxy)phenyl)-2-methylpropanoic acid;(2S)-3-[4-(tert-butoxy)phenyl]-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-2-methylpropanoic acid;MFCD32696669;Fmoc-(Me)Tyr(tBu)-OH;SCHEMBL25362437;AKOS005067684;AT30251;CS-0439220;(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-2-methyl-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]propanoic acid;

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cGMP Peptide
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  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C29H31NO5
M.W/Mr.
473.6
Sequence
Three Letter Code:Fmoc-aMeTyr(tBu)-OH
InChI
InChI=1S/C29H31NO5/c1-28(2,3)35-20-15-13-19(14-16-20)17-29(4,26(31)32)30-27(33)34-18-25-23-11-7-5-9-21(23)22-10-6-8-12-24(22)25/h5-16,25H,17-18H2,1-4H3,(H,30,33)(H,31,32)/t29-/m0/s1
InChI Key
GYJQWNBTHBMFNN-LJAQVGFWSA-N

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