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Amyloid β-Peptide (1-42) human

Amyloid β-Peptide (1-42) human is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
Amyloid β-Peptide (1-42) human(CAS 107761-42-2)

CAT No: R1193

CAS No:107761-42-2

Synonyms/Alias:β-Amyloid (1-42), human

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C203H311N55O60S
M.W/Mr.
4514.04
Sequence
One Letter Code: DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
Three Letter Code: Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-GIn-L ys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-lle-lle-Gly-Leu-Met-Val-Gly-Gly-Val-Val-lle-Ala
Biological Activity
Human form of the predominant amyloid β-peptide found in the brains of patients with Alzheimer's disease. Downregulates bcl-2 and increases the levels of bax. Neurotoxic.
Long-term Storage Conditions
Soluble to 1 mg/ml in 50mM Tris buffer
Shipping Condition
Room temperature in continental US; may vary elsewhere.

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