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  5. (Asn10,Leu11,D-Trp12)-pTH-Related Protein (7-34) amide (human, mouse, rat) H-Leu-Leu-His-Asn-Leu-D-Trp-Lys-Ser-Ile-Gln-Asp-Leu-Arg-Arg-Arg-Phe-Phe-Leu-His-His-Leu-Ile-Ala-Glu-Ile-His-Thr-Ala-NH2

(Asn10,Leu11,D-Trp12)-pTH-Related Protein (7-34) amide (human, mouse, rat) H-Leu-Leu-His-Asn-Leu-D-Trp-Lys-Ser-Ile-Gln-Asp-Leu-Arg-Arg-Arg-Phe-Phe-Leu-His-His-Leu-Ile-Ala-Glu-Ile-His-Thr-Ala-NH2

(Asn10,Leu11,D-Trp12)-pTH-Related Protein (7-34) amide (human, mouse, rat) carries targeted substitutions that reshape the pharmacophore of the parental peptide. Introduction of D-Trp modifies local geometry and proteolytic stability. Researchers quantify how these changes impact receptor engagement and secondary structure. Applications include antagonist-motif studies, peptide analog design, and receptor-mapping research.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: R2509

CAS No:129622-68-0

Synonyms/Alias:129622-68-0;(Asn10,Leu11,D-Trp12)-pTH-Related Protein (7-34) amide (human, mouse, rat) H-Leu-Leu-His-Asn-Leu-D-Trp-Lys-Ser-Ile-Gln-Asp-Leu-Arg-Arg-Arg-Phe-Phe-Leu-His-His-Leu-Ile-Ala-Glu-Ile-His-Thr-Ala-NH2;

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cGMP Peptide
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  • IND and NDA support
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M.F/Formula
C162H254N50O36
M.W/Mr.
3478.1
Sequence
One Letter Code:LLHNLWKSIQDLRRRFFLHHLIAEIHTA
Three Letter Code:H-Leu-Leu-His-Asn-Leu-D-Trp-Lys-Ser-Ile-Gln-Asp-Leu-Arg-Arg-Arg-Phe-Phe-Leu-His-His-Leu-Ile-Ala-Glu-Ile-His-Thr-Ala-NH2
InChI
InChI=1S/C162H254N50O36/c1-22-87(16)128(156(245)187-91(20)133(222)188-108(49-51-126(217)218)140(229)209-130(89(18)24-3)158(247)207-120(68-99-75-177-80-185-99)154(243)212-131(92(21)214)159(248)186-90(19)132(167)221)210-153(242)113(61-86(14)15)198-148(237)117(65-96-72-174-77-182-96)204-149(238)118(66-97-73-175-78-183-97)203-144(233)112(60-85(12)13)195-145(234)115(63-94-40-29-26-30-41-94)200-146(235)114(62-93-38-27-25-28-39-93)199-137(226)106(47-37-55-180-162(172)173)190-135(224)104(45-35-53-178-160(168)169)189-136(225)105(46-36-54-179-161(170)171)192-141(230)110(58-83(8)9)197-152(241)122(70-127(219)220)206-139(228)107(48-50-124(165)215)193-157(246)129(88(17)23-2)211-155(244)123(76-213)208-138(227)103(44-33-34-52-163)191-147(236)116(64-95-71-181-102-43-32-31-42-100(95)102)201-143(232)111(59-84(10)11)196-151(240)121(69-125(166)216)205-150(239)119(67-98-74-176-79-184-98)202-142(231)109(57-82(6)7)194-134(223)101(164)56-81(4)5/h25-32,38-43,71-75,77-92,101,103-123,128-131,181,213-214H,22-24,33-37,44-70,76,163-164H2,1-21H3,(H2,165,215)(H2,166,216)(H2,167,221)(H,174,182)(H,175,183)(H,176,184)(H,177,185)(H,186,248)(H,187,245)(H,188,222)(H,189,225)(H,190,224)(H,191,236)(H,192,230)(H,193,246)(H,194,223)(H,195,234)(H,196,240)(H,197,241)(H,198,237)(H,199,226)(H,200,235)(H,201,232)(H,202,231)(H,203,233)(H,204,238)(H,205,239)(H,206,228)(H,207,247)(H,208,227)(H,209,229)(H,210,242)(H,211,244)(H,212,243)(H,217,218)(H,219,220)(H4,168,169,178)(H4,170,171,179)(H4,172,173,180)/t87-,88-,89-,90-,91-,92+,101-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116+,117-,118-,119-,120-,121-,122-,123-,128-,129-,130-,131-/m0/s1
InChI Key
CXUJGNLXCFGLGT-HBVQLIPWSA-N

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