H-D-Pro-Phe-Arg-chloromethylketone trifluoroacetate salt incorporates a reactive chloromethylketone group for selective covalent modification of catalytic residues. Its aromatic and basic components influence substrate mimicry. The peptide is suited for mechanistic enzyme trapping and kinetic analysis. Applications include protease research and structure-activity studies.
CAT No: C0057
CAS No:88546-74-1
Synonyms/Alias:H-D-Pro-Phe-Arg-chloromethylketone;88546-74-1;(2R)-N-[(2S)-1-[[(3S)-1-chloro-6-(diaminomethylideneamino)-2-oxohexan-3-yl]amino]-1-oxo-3-phenylpropan-2-yl]pyrrolidine-2-carboxamide;D-Pro-Phe-Arg-Chloromethylketone;D-Pro-Phe-Arg chloromethyl ketone;H-D-Pro-Phe-Arg-chloromethylketone trifluoroacetate salt;CHEMBL521527;BDBM23569;DTXSID90440219;HY-P4245;D-Pro-Phe-Arg chloromethyl ketone (PCK);FP111023;CS-0653330;(2S)-N-[(3S)-6-carbamimidamido-1-chloro-2-oxohexan-3-yl]-3-phenyl-2-[(2R)-pyrrolidin-2-ylformamido]propanamide;(R)-N-((S)-1-((S)-1-chloro-6-guanidino-2-oxohexan-3-ylamino)-1-oxo-3-phenylpropan-2-yl)pyrrolidine-2-carboxamide;
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