substance P, Arg(1)-Pro(2)-Trp(7),(9)-LeuNH(2)(11)-

Substance P, Arg(1)-Pro(2)-Trp(7),(9)-LeuNH(2)(11)- contains targeted residue modifications that alter backbone flexibility and aromatic interactions. The sequence allows evaluation of steric effects on folding and receptor recognition. Researchers analyze its conformational shifts and binding characteristics. Applications include motif analysis, peptide engineering, and structure-activity studies.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
substance P, Arg(1)-Pro(2)-Trp(7),(9)-LeuNH(2)(11)-(CAS 84676-91-5)

CAT No: R2470

CAS No:84676-91-5

Synonyms/Alias:84676-91-5;Aptlsp;Substance P, arg(1)-pro(2)-trp(7),(9)-leunh(2)(11)-;D-Arg(1)-D-pro(2)-D-trp-7,9-leunh(2)(11)-substance P;DTXSID20233656;Argininyl(1)-prolyl(2)-tryptophyl-7,9-leucinamide(11)-substance P;(D-Arg1,D-Pro2,D-Trp7.9,Leu11)-Substance P;Substance P, 1-D-arginine-2-D-proline-7-D-tryptophan-9-D-tryptophan-11-L-leucinamide-;(D-ARG1,D-PRO2,D-TRP7,9,LEU11)-SUBSTANCE P;MFCD00076804;DTXCID50156147;DA-69133;FA108556;(D-Arg1,D-Pro2,D-Trp7?9,Leu11)-Substance P;H-D-Arg-D-Pro-Lys-Pro-Gln-Gln-D-Trp-Phe-D-Trp-Leu-Leu-NH2; H-(dR)(dP)KPQQ(dW)F(dW)LL-NH2;

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C75H108N20O13
M.W/Mr.
1497.8
Sequence
One Letter Code:RPKPQQWFWLL
Three Letter Code:H-D-Arg-D-Pro-Lys-Pro-Gln-Gln-D-Trp-Phe-D-Trp-Leu-Leu-NH2
InChI
InChI=1S/C75H108N20O13/c1-42(2)35-55(64(80)98)89-67(101)56(36-43(3)4)90-69(103)59(39-46-41-85-51-23-11-9-20-48(46)51)93-68(102)57(37-44-17-6-5-7-18-44)91-70(104)58(38-45-40-84-50-22-10-8-19-47(45)50)92-66(100)52(27-29-62(78)96)86-65(99)53(28-30-63(79)97)87-71(105)61-26-16-34-95(61)74(108)54(24-12-13-31-76)88-72(106)60-25-15-33-94(60)73(107)49(77)21-14-32-83-75(81)82/h5-11,17-20,22-23,40-43,49,52-61,84-85H,12-16,21,24-39,76-77H2,1-4H3,(H2,78,96)(H2,79,97)(H2,80,98)(H,86,99)(H,87,105)(H,88,106)(H,89,101)(H,90,103)(H,91,104)(H,92,100)(H,93,102)(H4,81,82,83)/t49-,52+,53+,54+,55+,56+,57+,58-,59-,60-,61+/m1/s1
InChI Key
SAPCBHPQLCZCDV-QVBDNUAOSA-N

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