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UP_Q1L777

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: X20507

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
Sequence
GCCSHPACSVNHPELC
Functions
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them. This synthetic peptide potently and reversibly blocks alpha-9/alpha-10 nAChR (IC(50)=6.9 nM). It reversibly blocks alpha-7 nAChR (IC(50)=1.8 nM). Is also active on alpha- 3/beta-2 (IC(50)=23 nM), alpha-3/beta-4 (IC(50)=480 nM) and alpha- 6/alpha3beta2beta3 nAChRs. Has little or no activity on alpha- 2/beta-4, alpha-2/beta-2, alpha-4/beta-2, alpha-4/beta-4 nAChRs.
Source#
Synthetic
Solubility
-20°C

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Creative Peptides is a trusted CDMO partner specializing in high-quality peptide synthesis, conjugation, and manufacturing under strict cGMP compliance. With advanced technology platforms and a team of experienced scientists, we deliver tailored peptide solutions to support drug discovery, clinical development, and cosmetic innovation worldwide.

From custom peptide synthesis to complex peptide-drug conjugates, we provide flexible, end-to-end services designed to accelerate timelines and ensure regulatory excellence. Our commitment to quality, reliability, and innovation has made us a preferred partner across the pharmaceutical, biotechnology, and personal care industries.

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