Acetyl-(Nle4,Asp5,D-Tyr7,Lys10)-cyclo-α-MSH (4-10) amide integrates hydrophobic, acidic, basic, and stereochemically inverted residues within a cyclic melanocortin framework. The acetyl and amide termini improve conformational homogeneity. Its compact ring supports precise analysis of receptor-binding determinants and backbone constraints. Applications include melanocortin ligand optimization and structure-activity studies.
2. Low bone turnover and low BMD in Down syndrome: effect of intermittent PTH treatment
3. Store-operated Ca2+ entry sustains the fertilization Ca2+ signal in pig eggs
4. Emu oil in combination with other active ingredients for treating skin imperfections
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