cAMP-Dependent Protein Kinase Inhibitor-α (5-22) amide (human, mouse, rabbit, rat)

Name: cAMP-Dependent Protein Kinase Inhibitor-α (5-22) amide (human, mouse, rabbit, rat)
Brand: Creative Peptides
SKU: P6403
Availability: MadeToOrder

cAMP-Dependent Protein Kinase Inhibitor-α (5-22) amide is a potent regulatory fragment used to probe structural determinants of kinase inhibition. Its ordered sequence targets the catalytic cleft of PKA, enabling detailed mechanistic study. Researchers employ it in assays investigating phosphorylation networks. The peptide supports modeling of kinase-substrate interactions across species.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: P6403

CAS No:100853-58-5

Synonyms/Alias:PKI-α (5-22) amide (human, mouse, rabbit, rat), Wiptide

Custom Peptide Synthesis

cGMP Peptide

Registration of APIs
CMC information required for an IND

IND and NDA support
Drug master files (DMF) filing

M.W/Mr.

1969.19

Sequence

H-Thr-Thr-Tyr-Ala-Asp-Phe-Ile-Ala-Ser-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-Ile-NH2

1. High fat diet and GLP-1 drugs induce pancreatic injury in mice

2. Low bone turnover and low BMD in Down syndrome: effect of intermittent PTH treatment

3. Uncarboxylated osteocalcin decreases insulin-stimulated glucose uptake without affecting insulin signaling and regulators of mitochondrial biogenesis in myotubes

4. GLP-1, exendin-4 and C-peptide regulate pancreatic islet microcirculation, insulin secretion and glucose tolerance in rats

5. The spatiotemporal control of signalling and trafficking of the GLP-1R

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