ISRIB is a small molecule with a bicyclic scaffold supporting studies of conformational rigidity and heterocycle-driven interactions. Its structure enables investigation of allosteric modulation, folding perturbation, and protein-ligand dynamics. Researchers employ it in exploring regulatory mechanisms and synthetic design principles. The compound's physicochemical profile supports extensive structural characterization.
CAT No: PI-015
CAS No:548470-11-7
Synonyms/Alias:ISRIB;1597403-47-8;trans-ISRIB;548470-11-7;ISRIB (trans-isomer);1597403-48-9;N,N'-(cis-Cyclohexane-1,4-diyl)bis(2-(4-chlorophenoxy)acetamide);ISRIB trans-isomer;2-(4-chlorophenoxy)-N-[4-[[2-(4-chlorophenoxy)acetyl]amino]cyclohexyl]acetamide;N,N'-(Cyclohexane-1,4-diyl)bis(2-(4-chlorophenoxy)acetamide);Integrated Stress Response inhibitor;N,N'-trans-1,4-cyclohexanediylbis[2-(4-chlorophenoxy)acetamide];Acetamide, N,N'-trans-1,4-cyclohexanediylbis[2-(4-chlorophenoxy)-;2-(4-chlorophenoxy)-N-[(1s,4s)-4-[2-(4-chlorophenoxy)acetamido]cyclohexyl]acetamide;2-(4-chlorophenoxy)-N-{4-[2-(4-chlorophenoxy)acetamido]cyclohexyl}acetamide;N,N'-(trans-cyclohexane-1,4-diyl)bis(2-(4-chlorophenoxy)acetamide);2-(4-chloranylphenoxy)-~{N}-[4-[2-(4-chloranylphenoxy)ethanoylamino]cyclohexyl]ethanamide;cis-ISRIB;N,N'-((1r,4r)-cyclohexane-1,4-diyl)bis(2-(4-chlorophenoxy)acetamide);C22H24Cl2N2O4;N,N'-trans-1,4-Cyclohexanediylbis[2-(4-chlorophenoxy)acetamide]; SMDC 750213;C7B;MFCD27952932;cis-ISRIB;ISRIB;ISRIB (cis-isomer);ISRIB?;S6SZR97SBZ;Oprea1_706389;AK-968/13065027;CHEMBL4303573;SCHEMBL16082980;SCHEMBL16082988;SCHEMBL16083047;EX-A298;CHEBI:232338;DTXSID601045380;GLXC-03636;HMS3887M19;SMDC750213;BCP10786;BCP23947;ISRIB, >=98% (HPLC);SMDC-750213;XNC40347;HY-12495A;s7400;STK435431;AKOS003300916;AKOS025142075;AKOS030633038;CCG-269245;2-(4-chlorophenoxy)-N-(4-{[(4-chlorophenoxy)acetyl]amino}cyclohexyl)acetamide;NCGC00384174-11;NCGC00384174-13;NCGC00389802-01;AC-35228;AS-16593;AS-55833;BI179448;DA-28222;DA-54475;DS-19940;CS-0029263;CS-0187553;S0706;C73020;BRD-K12826175-001-02-4;N,N'-cyclohexane-1,4-diylbis[2-(4-chlorophenoxy)acetamide];N,Na(2)-trans-1,4-Cyclohexanediylbis[2-(4-chlorophenoxy)acetamide];2-(4-chlorophenoxy)-N-[(1r,4r)-4-[2-(4-chlorophenoxy)acetamido]cyclohexyl]acetamide;
Chemical Name:2-(4-chlorophenoxy)-N-[4-[[2-(4-chlorophenoxy)acetyl]amino]cyclohexyl]acetamide
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