Obestatin is a hormone that is produced in specialized epithelial cells of the stomach and small intestine of several mammals including humans. Obestatin was originally identified as an anorectic peptide, but its effect on food intake remains controversial.
CAT No:10-101-65
CAS No:1081110-72-6
Synonyms/Alias:C16102; Obestatin
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M.F/Formula | C116H176N32O33 |
M.W/Mr. | 2546.87 |
Sequence | One Letter Code: FNAPFDVGIKLSGVQYQQHSQAL Three Letter Code: Phe-Asn-Ala-Pro-Phe-Asp-Val-Gly-Ile-Lys-Leu-Ser-Gly-Val-Gln-Tyr-Gln-Gln-His-Ser-Gln-Ala-Leu-NH2 |
Application | Obestatin opposes the actions of ghrelin which are growth hormone secretion and increased appetite. Obestatin has opposite action to ghrelin on food intake and plays a role in energy balance. Circuit-resistance exercise resulted in a significant change in GH levels, but had no effect on plasma Obestatin levels. |
Biological Activity | Obestatin (human) is an endogenous peptide derived from the same prepropeptide as ghrelin. Reported to suppress food intake and reduce body weight-gain in rats. |
Source# | Synthetic |
Shipping Condition | Shipped at 4°C. |
InChI Key | IXQOGPZNKNSCJR-QQDMDDJXSA-N |
1. SERS spectrum of the peptide thymosin‐β4 obtained with Ag nanorod substrate
3. Urinary Metabolites Associated with Blood Pressure on a Low-or High-Sodium Die
4. Cationic cell-penetrating peptides are potent furin inhibitors
5. The spatiotemporal control of signalling and trafficking of the GLP-1R
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