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Pentapeptide-3

Pentapeptide-3 is a synthetic peptide composed of five amino acids designed for use in cosmetic formulations targeting the appearance of aging skin. Its structure enables interaction with skin proteins, supporting improved skin texture and resilience. Suitable for a range of topical applications, Pentapeptide-3 is compatible with various formulation types and can be incorporated into serums, creams, and emulsions intended for daily skin care routines.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CPC1611

CAS No:135679-88-8; 725232-44-0 (RS)

Synonyms/Alias:Vialox Peptide; Vialox; Pentapeptide 3

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C21H37N9O5
M.W/Mr.
495.58
Sequence
H-Gly-Pro-Arg-Pro-Ala-OH
Purity
>98 %
Functions
Pentapeptide-3 is a topical alternative to muscle relaxing injections. It's an intensive anti-wrinkle care, especially for the fighting against expression lines.

Mechanism of Action (MOA)

Pentapeptide-3 is a synthetic signal peptide composed of five amino acids. It is designed to mimic a fragment of the SNAP-25 protein, which is involved in the regulation of neurotransmitter release at the neuromuscular junction. By interacting with the SNARE complex, Pentapeptide-3 can modulate neuronal signaling pathways, supporting a relaxed appearance in skin by influencing the communication between nerve endings and target cells.

Pentapeptide-3 is suitable for incorporation into a variety of topical cosmetic formulations.

- Facial serums for daily skincare routines
- Lightweight moisturizers and emulsions
- Eye creams and targeted treatment products
- Sheet masks and leave-on treatments
- Primers and makeup bases
- Night creams and restorative formulations
- Ampoules and concentrated boosters

INCIName
Pentapeptide-3
Shipping Condition
Room temperature
InChI
InChI=1S/C21H37N9O5/c1-12(17(23)32)27-18(33)15-7-4-10-30(15)20(35)13(5-2-8-26-21(24)25)28-19(34)14-6-3-9-29(14)16(31)11-22/h12-15H,2-11,22H2,1H3,(H2,23,32)(H,27,33)(H,28,34)(H4,24,25,26)/t12-,13-,14-,15-/m0/s1
InChI Key
BYWJFRMLHFQWSR-AJNGGQMLSA-N
Canonical SMILES
CC(C(=O)N)NC(=O)C1CCCN1C(=O)C(CCCN=C(N)N)NC(=O)C2CCCN2C(=O)CN
Isomeric SMILES
C[C@@H](C(=O)N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H]2CCCN2C(=O)CN
References
Vialox

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