TFLLR-NH2

TFLLR-NH2 is a selective PAR1 agonist with an EC50 of 1.9 μM.

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CAT No: R1713

CAS No: 197794-83-5

Synonyms/Alias: TFLLR-NH2;197794-83-5;Thr-Phe-Leu-Leu-Arg-amide;(2S)-N-[(2S)-1-[[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-[[(2S)-2-[[(2S,3R)-2-amino-3-hydroxybutanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanamide;H-Thr-Phe-Leu-Leu-Arg-NH2;PAR1-AP;GTPL3742;CHEMBL4065100;L-Argininamide, L-threonyl-L-phenylalanyl-L-leucyl-L-leucyl-;HY-P0226;HB2921;AKOS024456615;CS-6494;TFLLR (modifications: C-terminal amide);AC-32571;AS-76215;DA-48902;FT109632;PEPTIDE1{T.F.L.L.R.[am]}$$$$;(Thr1)-PAR-1 (1-5) amide (human) trifluoroacetate salt;l-threonyl-l-phenylalanyl-l-leucyl-l-leucyl-l-argininamide;(2S)-2-[(2S)-2-[(2S,3R)-2-amino-3-hydroxybutanamido]-3-phenylpropanamido]-N-[(1S)-1-{[(1S)-4-carbamimidamido-1-carbamoylbutyl]carbamoyl}-3-methylbutyl]-4-methylpentanamide;TFLLRamide, (Thr(1))-TRAP-5 amide, TFLLR-NH2 Protease-Activated Receptor 1 (PAR1) Agonist;(Thr1)-PAR-1 (1-5) amide (human);

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Specification Technical Data Publications Customer reviews and Q&A
M.F/FormulaC31H53N9O6
M.W/Mr.647.8
SequenceOne Letter Code:TFLLR
Three Letter Code:H-Thr-Phe-Leu-Leu-Arg-NH2
Shipping ConditionRoom temperature in continental US; may vary elsewhere.
InChIInChI=1S/C31H53N9O6/c1-17(2)14-22(27(43)37-21(26(33)42)12-9-13-36-31(34)35)38-28(44)23(15-18(3)4)39-29(45)24(16-20-10-7-6-8-11-20)40-30(46)25(32)19(5)41/h6-8,10-11,17-19,21-25,41H,9,12-16,32H2,1-5H3,(H2,33,42)(H,37,43)(H,38,44)(H,39,45)(H,40,46)(H4,34,35,36)/t19-,21+,22+,23+,24+,25+/m1/s1
InChI KeyANAMCEKSRDPIPX-GFGQVAFXSA-N

1. Therapeutic potential of an intestinotrophic hormone, glucagon-like peptide 2, for treatment of type 2 short bowel syndrome rats with intestinal bacterial and fungal dysbiosis

2. An Isolated TCR αβ Restricted by HLA-A* 02: 01/CT37 Peptide Redirecting CD8+ T Cells to Kill and Secrete IFN-γ in Response to Lung Adenocarcinoma Cell Lines

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