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UP_P0C1D0

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: X18045

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
Sequence
GCCSDPRCRYRC
Functions
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them. Is a specific blocker of the alpha-9/alpha-10 nAChR. Is also active on alpha-7 (but 1000-fold less potent) and on alpha-2/beta-2, alpha-2/beta-4, alpha-3/beta-4, alpha-3/beta-2, alpha-4/beta-2, alpha-4/beta-4 and alpha-6/alpha-3beta-2beta-3 (but 2000-fold less potent) channels.
Source#
Synthetic
Solubility
-20°C

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