Name: UP_P0C1H1
Brand: Creative Peptides
SKU: X18047
Availability: MadeToOrder

Sequence

SVAVAGAVIEGATLTFNVLQ

Functions

This cardiac stimulatory and hemolytic pore-forming protein forms cations-selective hydrophilic pores of around 1 nm. Cytolytic effects include red blood cells hemolysis, platelet aggregation and lysis, cytotoxic and cytostatic effects on fibroblasts. Lethality in mammals has been ascribed to severe vasospasm of coronary vessels, cardiac arrhythmia, and inotropic effects. Pore formation proceeds by membrane binding via a surface rich in aromatic residues, followed by translocation of the N- terminal region to the membrane and, finally, across the bilayer to form a functional pore (By similarity).

Source#

Synthetic

Solubility

-20°C

1. Exosomes-mediated Transfer of miR-125a/b in Cell-to-cell Communication: A Novel Mechanism of Genetic Exchange in the Intestinal Microenvironment

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3. Peptides as Active Ingredients: A Challenge for Cosmeceutical Industry

4. Multifunctional peptide-oligonucleotide conjugate promoted sensitive electrochemical biosensing of cardiac troponin I

5. Low bone turnover and low BMD in Down syndrome: effect of intermittent PTH treatment